Chemical Compound Review:
clindamycin N-[2-chloro-1-(3,4,5- trihydroxy-6...
Synonyms:
AG-C-17669, SureCN12356681, AC1L1EGQ, BBL005238, CTK6D4956, ...
Ugwumadu,
Manyonda,
Reid,
Hay,
Mayer,
Bersoff-Matcha,
Murphy,
Earls,
Harper,
Pauze,
Nguyen,
Rosenthal,
Cerva,
Druckenbrod,
Hanfling,
Fatteh,
Napoli,
Nayyar,
Berman,
Krause,
Lepore,
Sikand,
Gadbaw,
Burke,
Telford,
Brassard,
Pearl,
Azlanzadeh,
Christianson,
McGrath,
Spielman,
Johnson,
Samore,
Farrow,
Killgore,
Tenover,
Lyras,
Rood,
DeGirolami,
Baltch,
Rafferty,
Pear,
Gerding,
Vaara,
Nurminen,
- Epidemics of diarrhea caused by a clindamycin-resistant strain of Clostridium difficile in four hospitals. Johnson, S., Samore, M.H., Farrow, K.A., Killgore, G.E., Tenover, F.C., Lyras, D., Rood, J.I., DeGirolami, P., Baltch, A.L., Rafferty, M.E., Pear, S.M., Gerding, D.N. N. Engl. J. Med. (1999)
- Risk of infection after penetrating abdominal trauma. Nichols, R.L., Smith, J.W., Klein, D.B., Trunkey, D.D., Cooper, R.H., Adinolfi, M.F., Mills, J. N. Engl. J. Med. (1984)
- Toxoplasmic encephalitis in patients with the acquired immunodeficiency syndrome. Members of the ACTG 077p/ANRS 009 Study Team. Luft, B.J., Hafner, R., Korzun, A.H., Leport, C., Antoniskis, D., Bosler, E.M., Bourland, D.D., Uttamchandani, R., Fuhrer, J., Jacobson, J. N. Engl. J. Med. (1993)
- Atovaquone and azithromycin for the treatment of babesiosis. Krause, P.J., Lepore, T., Sikand, V.K., Gadbaw, J., Burke, G., Telford, S.R., Brassard, P., Pearl, D., Azlanzadeh, J., Christianson, D., McGrath, D., Spielman, A. N. Engl. J. Med. (2000)
- Persistent parasitemia after acute babesiosis. Krause, P.J., Spielman, A., Telford, S.R., Sikand, V.K., McKay, K., Christianson, D., Pollack, R.J., Brassard, P., Magera, J., Ryan, R., Persing, D.H. N. Engl. J. Med. (1998)
- Antimicrobial prophylaxis for contaminated head and neck surgery. Johnson, J.T., Myers, E.N., Thearle, P.B., Sigler, B.A., Schramm, V.L. Laryngoscope (1984)
- Action of clindamycin-phosphate in foreign body infections due to Staphylococcus epidermidis in mice. Fichera, G.A., Pappalardo, C., Nicolosi, V.M., Gismondo, M.R., Stefani, S., Nicoletti, G. Chemioterapia : international journal of the Mediterranean Society of Chemotherapy. (1987)
- A plastid organelle as a drug target in apicomplexan parasites. Fichera, M.E., Roos, D.S. Nature (1997)
- Macrolide resistance among invasive Streptococcus pneumoniae isolates. Hyde, T.B., Gay, K., Stephens, D.S., Vugia, D.J., Pass, M., Johnson, S., Barrett, N.L., Schaffner, W., Cieslak, P.R., Maupin, P.S., Zell, E.R., Jorgensen, J.H., Facklam, R.R., Whitney, C.G. JAMA (2001)
- Subtotal colectomy for refractory pseudomembranous enterocolitis. Boyd, W.C., DenBesten, L. JAMA (1976)
- Clinical presentation of inhalational anthrax following bioterrorism exposure: report of 2 surviving patients. Mayer, T.A., Bersoff-Matcha, S., Murphy, C., Earls, J., Harper, S., Pauze, D., Nguyen, M., Rosenthal, J., Cerva, D., Druckenbrod, G., Hanfling, D., Fatteh, N., Napoli, A., Nayyar, A., Berman, E.L. JAMA (2001)
- Prevention of recurrent staphylococcal skin infections with low-dose oral clindamycin therapy. Klempner, M.S., Styrt, B. JAMA (1988)
- Acute osteomyelitis in a district general hospital. Glover, S.C., McKendrick, M.W., Padfield, C., Geddes, A.M., Dwyer, N.S. Lancet (1982)
- Microbial causes of proven pelvic inflammatory disease and efficacy of clindamycin and tobramycin. Wasserheit, J.N., Bell, T.A., Kiviat, N.B., Wølner-Hanssen, P., Zabriskie, V., Kirby, B.D., Prince, E.C., Holmes, K.K., Stamm, W.E., Eschenbach, D.A. Ann. Intern. Med. (1986)
- Potentiation of opsonization and phagocytosis of Streptococcus pyogenes following growth in the presence of clindamycin. Gemmell, C.G., Peterson, P.K., Schmeling, D., Kim, Y., Mathews, J., Wannamaker, L., Quie, P.G. J. Clin. Invest. (1981)
- Effect of early oral clindamycin on late miscarriage and preterm delivery in asymptomatic women with abnormal vaginal flora and bacterial vaginosis: a randomised controlled trial. Ugwumadu, A., Manyonda, I., Reid, F., Hay, P. Lancet (2003)
- Combination effects of ciprofloxacin, clindamycin, and metronidazole intravenously in volunteers. Deppermann, K.M., Boeckh, M., Grineisen, S., Shokry, F., Borner, K., Koeppe, P., Krasemann, C., Wagner, J., Lode, H. Am. J. Med. (1989)
- Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin. Schlünzen, F., Pyetan, E., Fucini, P., Yonath, A., Harms, J.M. Mol. Microbiol. (2004)
- Clinical risk factors for prolonged PT/PTT in abdominal sepsis patients treated with moxalactam or tobramycin plus clindamycin. Baxter, J.G., Marble, D.A., Whitfield, L.R., Wels, P.B., Walczak, P., Schentag, J.J. Ann. Surg. (1985)
- Inhibition of cytoplasmic and organellar protein synthesis in Toxoplasma gondii. Implications for the target of macrolide antibiotics. Beckers, C.J., Roos, D.S., Donald, R.G., Luft, B.J., Schwab, J.C., Cao, Y., Joiner, K.A. J. Clin. Invest. (1995)
- Role of clostridial toxin in the pathogenesis of clindamycin colitis in rabbits. LaMont, J.T., Sonnenblick, E.B., Rothman, S. Gastroenterology (1979)
- Effect of clindamycin on intestinal water and glucose transport in the rat. Giannella, R.A., Serumaga, J., Walls, D., Drake, K.W. Gastroenterology (1981)
- Gastrointestinal and systemic toxicity of fecal extracts from hamsters with clindamycin-induced colitis. Rifkin, G.D., Silva, J., Fekety, R. Gastroenterology (1978)
- Resistance to methicillin and other antibiotics in isolates of Staphylococcus aureus from blood and cerebrospinal fluid, England and Wales, 1989-95. Speller, D.C., Johnson, A.P., James, D., Marples, R.R., Charlett, A., George, R.C. Lancet (1997)
- Tissue concentration of clindamycin and gentamicin near ischaemic ulcers with transvenous injection in Bier's arterial arrest. Burgmann, H., Georgopoulos, A., Graninger, W., Koppensteiner, R., Maca, T., Minar, E., Schneider, B., Stümpflen, A., Ehringer, H. Lancet (1996)
- Inhibition of neutrophil oxidative metabolism by lysosomotropic weak bases. Styrt, B., Klempner, M.S. Blood (1986)
- Inactivation of lincosaminide antibiotics in Staphylococcus. Identification of lincosaminide O-nucleotidyltransferases and comparison of the corresponding resistance genes. Brisson-Noël, A., Delrieu, P., Samain, D., Courvalin, P. J. Biol. Chem. (1988)
- Clindamycin suppresses endotoxin released by ceftazidime-treated Escherichia coli O55:B5 and subsequent production of tumor necrosis factor alpha and interleukin-1 beta. Kishi, K., Hirai, K., Hiramatsu, K., Yamasaki, T., Nasu, M. Antimicrob. Agents Chemother. (1999)
- Suppression of Gastric Acid Production by Proton Pump Inhibitor Treatment Facilitates Colonization of the Large Intestine by Vancomycin-Resistant Enterococcus spp. and Klebsiella pneumoniae in Clindamycin-Treated Mice. Stiefel, U., Rao, A., Pultz, M.J., Jump, R.L., Aron, D.C., Donskey, C.J. Antimicrob. Agents Chemother. (2006)
- Outer membrane permeability barrier in Escherichia coli mutants that are defective in the late acyltransferases of lipid A biosynthesis. Vaara, M., Nurminen, M. Antimicrob. Agents Chemother. (1999)
- In vitro metabolism of clindamycin in human liver and intestinal microsomes. Wynalda, M.A., Hutzler, J.M., Koets, M.D., Podoll, T., Wienkers, L.C. Drug Metab. Dispos. (2003)
- Prevention of clindamycin-induced colitis in hamsters by Clostridium sordellii antitoxin. Allo, M., Silva, J., Fekety, R., Rifkin, G.D., Waskin, H. Gastroenterology (1979)