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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Mackay, I.M. et al.

Mackay, Bialasiewicz, Jacob, McQueen, Arden, Nissen, Sloots,

Genetic diversity of human metapneumovirus over 4 consecutive years in Australia.

The molecular epidemiologic profile of human metapneumovirus (hMPV) infection has likely been skewed toward certain genetic subtypes because of assay-design issues, and no comprehensive studies have been conducted to date. Here, reverse-transcription polymerase chain reaction was used to screen 10,319 specimens from patients presenting to hospitals with suspected respiratory tract infections during 2001-2004. After analysis of 727 Australian hMPV strains, 640 were assigned to 1 of 4 previously described subtypes. hMPV was the most common pathogen detected, and subtype B1 was the most common lineage. Concurrent, annual circulation of all 4 hMPV subtypes in our study population was common, with a single, usually different hMPV subtype predominating in each year.[1]

References

Genetic diversity of human metapneumovirus over 4 consecutive years in Australia. Mackay, I.M., Bialasiewicz, S., Jacob, K.C., McQueen, E., Arden, K.E., Nissen, M.D., Sloots, T.P. J. Infect. Dis. (2006) [Pubmed]

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