- Low expression of the snail gene is a good prognostic factor in node-negative invasive ductal carcinomas. Toyama, T., Zhang, Z., Iwase, H., Yamashita, H., Ando, Y., Hamaguchi, M., Mizutani, M., Kondo, N., Fujita, T., Fujii, Y., Iwata, H. Jpn. J. Clin. Oncol. (2006)