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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Activity of retapamulin (SB-275833), a novel pleuromutilin, against selected resistant gram-positive cocci.

Retapamulin (SB-275833), the first pleuromutilin to be developed for human topical use, was tested against a selected population of staphylococci and beta-hemolytic streptococci. The MIC90 results for retapamulin were 0.12 microg/ml for Staphylococcus aureus and < or = 0.03 microg/ml for Streptococcus pyogenes; no cross-resistance was observed for organism subsets resistant to oxacillin, erythromycin, or mupirocin.[1]

References

  1. Activity of retapamulin (SB-275833), a novel pleuromutilin, against selected resistant gram-positive cocci. Jones, R.N., Fritsche, T.R., Sader, H.S., Ross, J.E. Antimicrob. Agents Chemother. (2006) [Pubmed]
 
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