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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Alternative procedure for the synthesis of Mansonone F and Biflorin precursor.

Synthetic studies on Mansonone F and Biflorin are described. Synthesis of ketone 12 has been achieved by utilizing tetrahydronaphthalene 8 which in turn was prepared from the 5-methoxy-alpha-tetralone 3. The conversion of 8 into ketone 12 was accomplished in four steps (O-alkylation with ethyl bromoacetate, dehydrogenation, alkaline hydrolysis and cyclization with phosponate ester).[1]

References

  1. Alternative procedure for the synthesis of Mansonone F and Biflorin precursor. Ng, P.S., Banerjee, A.K. Nat. Prod. Res. (2006) [Pubmed]
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