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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Genetic Environment of Acquired blaACC-1 {beta}-Lactamase Gene in Enterobacteriaceae Isolates.

We studied the genetic organization of bla(ACC-1) in 14 isolates of Enterobacteriaceae from France, Tunisia, and Germany. In a common ancestor, ISEcp1 was likely involved in the mobilization of this gene from the Hafnia alvei chromosome to a plasmid. Other genetic events involving insertion sequences (particularly IS26), transposons (particularly Tn1696), or sulI-type integrons have occurred, leading to complex genetic environments.[1]


  1. Genetic Environment of Acquired blaACC-1 {beta}-Lactamase Gene in Enterobacteriaceae Isolates. Doloy, A., Verdet, C., Gautier, V., Decr??, D., Ronco, E., Hammami, A., Philippon, A., Arlet, G. Antimicrob. Agents Chemother. (2006) [Pubmed]
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