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Majerus, S. et al.

Steve Majerus, Martial Van der Linden, Vérane Braissand, Stephan Eliez,

Verbal short-term memory in individuals with chromosome 22q11.2 deletion: specific deficit in serial order retention capacities?

Many researchers have recently explored the cognitive profile of velocardiofacial syndrome (VCFS), a neurodevelopmental disorder linked to a 22q11.2 deletion. However, verbal short-term memory has not yet been systematically investigated. We explored verbal short-term memory abilities in a group of 11 children and adults presenting with VCFS and two control groups, matched on either CA or vocabulary knowledge, by distinguishing short-term memory for serial order and item information. The VCFS group showed impaired performance on the serial order short-term memory tasks compared to both control groups. Relative to the vocabulary-matched control group, item short-term memory was preserved. The implication of serial order short-term memory deficits on other aspects of cognitive development in VCFS (e.g., language development, numerical cognition) is discussed.[1]

References

Verbal short-term memory in individuals with chromosome 22q11.2 deletion: specific deficit in serial order retention capacities? Majerus, S., Van der Linden, M., Braissand, V., Eliez, S. Am. J. Ment. Retard (2007) [Pubmed]

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