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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Histochemistry of oxidative enzymes in experimental allergic encephalomyelitis.

The histoenzymic pattern of oxidative enzymes (G3PD, IDH, SD, G6PD,HBD, NADPH: dehydrogenase) was investigated in experimental allergic encephalomyelitis (EAE) produced in rats according to PATERSON [13]. The results obtained lead to following conclusions: (1) The neuroglia, including the white matter oligodendroglia of immunized rats, exhibits increased oxidoreductase activities; (2) The neuroallergic reaction induces some stimulation of the oxidoreductive metabolism of oligoden-droglia; (3) The enzymatic hyperactivity in EAE does not show any relation to the morphological signs of alterations of the myelin sheath.[1]


  1. Histochemistry of oxidative enzymes in experimental allergic encephalomyelitis. Wender, M., Kozik, M., Goncerzewicz, A. Folia histochemica et cytochemica. (1976) [Pubmed]
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