Chemical Compound Review:
NADP(H) [5-[[[[5-(3-aminocarbonyl-4H- pyridin-1-yl)...
Synonyms:
AGN-PC-00IQUU, KST-1A5818, AC1L1ACH, AC1Q5IRF, AR-1A9125, ...
- Genetic variants of chronic granulomatous disease: prevalence of deficiencies of two cytosolic components of the NADPH oxidase system. Clark, R.A., Malech, H.L., Gallin, J.I., Nunoi, H., Volpp, B.D., Pearson, D.W., Nauseef, W.M., Curnutte, J.T. N. Engl. J. Med. (1989)
- Nitric oxide synthase activity in infantile hypertrophic pyloric stenosis. Vanderwinden, J.M., Mailleux, P., Schiffmann, S.N., Vanderhaeghen, J.J., De Laet, M.H. N. Engl. J. Med. (1992)
- Enx (Hox11L1)-deficient mice develop myenteric neuronal hyperplasia and megacolon. Shirasawa, S., Yunker, A.M., Roth, K.A., Brown, G.A., Horning, S., Korsmeyer, S.J. Nat. Med. (1997)
- Twists in catalysis: alternating conformations of Escherichia coli thioredoxin reductase. Lennon, B.W., Williams, C.H., Ludwig, M.L. Science (2000)
- Antimicrobial actions of the NADPH phagocyte oxidase and inducible nitric oxide synthase in experimental salmonellosis. II. Effects on microbial proliferation and host survival in vivo. Mastroeni, P., Vazquez-Torres, A., Fang, F.C., Xu, Y., Khan, S., Hormaeche, C.E., Dougan, G. J. Exp. Med. (2000)
- Quantitative evolutionary design of glucose 6-phosphate dehydrogenase expression in human erythrocytes. Salvador, A., Savageau, M.A. Proc. Natl. Acad. Sci. U.S.A. (2003)
- Mechanistic basis for nonlinear kinetics of aldehyde reduction catalyzed by aldose reductase. Grimshaw, C.E., Shahbaz, M., Putney, C.G. Biochemistry (1990)
- Neuronal overexpression of heme oxygenase-1 correlates with an attenuated exploratory behavior and causes an increase in neuronal NADPH diaphorase staining. Maines, M.D., Polevoda, B., Coban, T., Johnson, K., Stoliar, S., Huang, T.J., Panahian, N., Cory-Slechta, D.A., McCoubrey, W.K. J. Neurochem. (1998)
- Compartmental loss of NADPH diaphorase in the neuropil of the human striatum in Huntington's disease. Morton, A.J., Nicholson, L.F., Faull, R.L. Neuroscience (1993)
- NADPH diaphorase histochemistry of the human hypothalamus. Sangruchi, T., Kowall, N.W. Neuroscience (1991)
- The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Bedard, K., Krause, K.H. Physiol. Rev. (2007)
- Pathogen-induced, NADPH oxidase-derived reactive oxygen intermediates suppress spread of cell death in Arabidopsis thaliana. Torres, M.A., Jones, J.D., Dangl, J.L. Nat. Genet. (2005)
- Metabolic regulation of oocyte cell death through the CaMKII-mediated phosphorylation of caspase-2. Nutt, L.K., Margolis, S.S., Jensen, M., Herman, C.E., Dunphy, W.G., Rathmell, J.C., Kornbluth, S. Cell (2005)
- Mutations in the genes encoding 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency. Draper, N., Walker, E.A., Bujalska, I.J., Tomlinson, J.W., Chalder, S.M., Arlt, W., Lavery, G.G., Bedendo, O., Ray, D.W., Laing, I., Malunowicz, E., White, P.C., Hewison, M., Mason, P.J., Connell, J.M., Shackleton, C.H., Stewart, P.M. Nat. Genet. (2003)
- Pyridine nucleotide-dependent superoxide production by a cell-free system from human granulocytes. Babior, B.M., Curnutte, J.T., Kipnes, B.S. J. Clin. Invest. (1975)
- Relationship between metabolic clearance rate of antipyrine and hepatic microsomal drug-oxidizing enzyme activities in humans without liver disease. Vuitton, D., Miguet, J.P., Camelot, G., Delafin, C., Joanne, C., Bechtel, P., Gillet, M., Carayon, P. Gastroenterology (1981)
- Hydrogen donor system for Escherichia coli ribonucleoside-diphosphate reductase dependent upon glutathione. Holmgren, A. Proc. Natl. Acad. Sci. U.S.A. (1976)
- Bidirectional regulation of osteoclast function by nitric oxide synthase isoforms. Brandi, M.L., Hukkanen, M., Umeda, T., Moradi-Bidhendi, N., Bianchi, S., Gross, S.S., Polak, J.M., MacIntyre, I. Proc. Natl. Acad. Sci. U.S.A. (1995)
- Identification of Ald6p as the target of a class of small-molecule suppressors of FK506 and their use in network dissection. Butcher, R.A., Schreiber, S.L. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1. Abo, A., Pick, E., Hall, A., Totty, N., Teahan, C.G., Segal, A.W. Nature (1991)
- Reactive oxygen species produced by NADPH oxidase regulate plant cell growth. Foreman, J., Demidchik, V., Bothwell, J.H., Mylona, P., Miedema, H., Torres, M.A., Linstead, P., Costa, S., Brownlee, C., Jones, J.D., Davies, J.M., Dolan, L. Nature (2003)
- Atomic structure of ferredoxin-NADP+ reductase: prototype for a structurally novel flavoenzyme family. Karplus, P.A., Daniels, M.J., Herriott, J.R. Science (1991)
- Nitric oxide mediates network oscillations of olfactory interneurons in a terrestrial mollusc. Gelperin, A. Nature (1994)
- Priming of neutrophils for enhanced release of oxygen metabolites by bacterial lipopolysaccharide. Evidence for increased activity of the superoxide-producing enzyme. Guthrie, L.A., McPhail, L.C., Henson, P.M., Johnston, R.B. J. Exp. Med. (1984)
- NADPH-binding component of the respiratory burst oxidase system: studies using neutrophil membranes from patients with chronic granulomatous disease lacking the beta-subunit of cytochrome b558. Tsunawaki, S., Mizunari, H., Namiki, H., Kuratsuji, T. J. Exp. Med. (1994)
- Novel NADPH-binding domain revealed by the crystal structure of aldose reductase. Rondeau, J.M., Tête-Favier, F., Podjarny, A., Reymann, J.M., Barth, P., Biellmann, J.F., Moras, D. Nature (1992)
- Components of sterol biosynthesis assembled on the oxygen-avid hemoglobin of Ascaris. Sherman, D.R., Guinn, B., Perdok, M.M., Goldberg, D.E. Science (1992)
- Properties and biological activities of thioredoxins. Powis, G., Montfort, W.R. Annu. Rev. Pharmacol. Toxicol. (2001)
- Manganese-dependent NADPH oxidation by granulocyte particles. The role of superoxide and the nonphysiological nature of the manganese requirement. Curnutte, J.T., Karnovsky, M.L., Babior, B.M. J. Clin. Invest. (1976)
- Proton secretion by the sodium/hydrogen ion antiporter in the human neutrophil. Wright, J., Schwartz, J.H., Olson, R., Kosowsky, J.M., Tauber, A.I. J. Clin. Invest. (1986)
- A novel NADH kinase is the mitochondrial source of NADPH in Saccharomyces cerevisiae. Outten, C.E., Culotta, V.C. EMBO J. (2003)
- Unexpected genetic and structural relationships of a long-forgotten flavoenzyme to NAD(P)H:quinone reductase (DT-diaphorase). Zhao, Q., Yang, X.L., Holtzclaw, W.D., Talalay, P. Proc. Natl. Acad. Sci. U.S.A. (1997)
- Neural roles for heme oxygenase: contrasts to nitric oxide synthase. Barañano, D.E., Snyder, S.H. Proc. Natl. Acad. Sci. U.S.A. (2001)
- Modulation of ion channels in rod photoreceptors by nitric oxide. Kurenny, D.E., Moroz, L.L., Turner, R.W., Sharkey, K.A., Barnes, S. Neuron (1994)
- Molecular cloning and characterization of the constitutive bovine aortic endothelial cell nitric oxide synthase. Nishida, K., Harrison, D.G., Navas, J.P., Fisher, A.A., Dockery, S.P., Uematsu, M., Nerem, R.M., Alexander, R.W., Murphy, T.J. J. Clin. Invest. (1992)
- Impaired expression of nitric oxide synthase in the gastric myenteric plexus of spontaneously diabetic rats. Takahashi, T., Nakamura, K., Itoh, H., Sima, A.A., Owyang, C. Gastroenterology (1997)
- Neuronal NADPH diaphorase is a nitric oxide synthase. Hope, B.T., Michael, G.J., Knigge, K.M., Vincent, S.R. Proc. Natl. Acad. Sci. U.S.A. (1991)
- Structure and mechanism of mammalian thioredoxin reductase: the active site is a redox-active selenolthiol/selenenylsulfide formed from the conserved cysteine-selenocysteine sequence. Zhong, L., Arnér, E.S., Holmgren, A. Proc. Natl. Acad. Sci. U.S.A. (2000)