Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Warshaw, E.M. et al.

Contact dermatitis associated with food: retrospective cross-sectional analysis of North American Contact Dermatitis Group data, 2001-2004.

BACKGROUND: Allergic and irritant contact dermatitis to food is likely underreported. OBJECTIVES: To characterize relevant allergens and irritants associated with food in patients referred to the North American Contact Dermatitis Group (NACDG) for patch testing. METHODS: Retrospective analysis of cross-sectional data from the NACDG from 2001 to 2004. RESULTS: Of 10,061 patch-tested patients, 109 (1.1%) had a total of 122 reactions associated with food. Approximately two-thirds of patients (66%) were female, and one-third (36%) were atopic. The hands were the most common sites of dermatitis (36.7%). There were 78 currently relevant (definite, probable, or possible) allergic reactions to NACDG standard series allergens with a food source; the most common allergen was nickel (48.7%), followed by Myroxilon pereirae (balsam of Peru) (20.6%) and propylene glycol (6.4%). Twenty allergic reactions to non-NACDG standard allergens and 24 relevant food irritants were also identified. Overall, 21% (25 of 122) of all reactions (irritant and allergic) were occupation related; the majority of these (17 of 25) were relevant irritant reactions. Cooks were the most commonly affected occupational group (40%). CONCLUSIONS: In this limited data set, nickel, Myroxilon pereirae, and propylene glycol were the most common allergens identified with a food source. Of food-related occupational disease, irritation was more common than allergy.[1]

References

Contact dermatitis associated with food: retrospective cross-sectional analysis of North American Contact Dermatitis Group data, 2001-2004. Warshaw, E.M., Botto, N.C., Zug, K.A., Belsito, D.V., Maibach, H.I., Sasseville, D., Fowler, J.F., Storrs, F.J., Taylor, J.S., DeLeo, V.A., Marks, J.G., Mathias, C.G., Pratt, M.D., Rietschel, R.L. Dermatitis (2008) [Pubmed]

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