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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Subcellular distribution of the tumor-specific transplantation antigen of simian virus 40-transformed cells.

TU-5, a simian virus 40 (SV40)-transformed cell line of BALB/c origin, expressed the SV40-specific T-antigen and a transplantation antigen ( TSTA). Nuclei and plasma membranes were prepared from these cells and shown on the basis of the distribution of T-antigen and histocompatibility ( H-2) antigens to be relatively free of cross contamination. Most of the TSTA, estimated by tumor rejection, was associated with the nuclear fraction.[1]


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