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Bowcock, A.M. et al.

Anne M. Bowcock, Marcelo Fernandez-Vina,

Targeting skin: vitiligo and autoimmunity.

In this issue, Singh and co-workers describe the results of classical typing of human leukocyte antigen (HLA) alleles in 1,404 vitiligo patients and 902 unaffected controls from North India and follow-up HLA typing in 355 cases and 441 controls from Gujarat. The increased frequency of DRB1*07:01 in North Indian and Gujarat populations with generalized and localized vitiligo and in several vitiligo populations studied previously suggests that it contributes to autoimmunity and destruction of melanocytes.[1]

References

Targeting skin: vitiligo and autoimmunity. Bowcock, A.M., Fernandez-Vina, M. J. Invest. Dermatol. (2012) [Pubmed]

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