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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Cocaine/"crack" dependence among psychiatric inpatients.

The authors studied 40 cocaine-dependent subjects admitted to psychiatric inpatient wards of a metropolitan hospital because of general psychiatric symptoms. The results indicate that the predominant form of cocaine administration (88%) was freebasing "crack." DSM-III-R cluster B personality disorders (N = 17) and schizophrenia (N = 13) constituted the diagnoses for 75% of the sample. Compared to the schizophrenic patients in this cohort, the patients with cluster B personality disorders used cocaine in greater quantities and more frequently and began abuse of the drug at an earlier age. The escalation in urban areas of psychiatric hospitalizations attributed to use of crack may be largely related to psychiatric symptoms in cocaine-dependent patients with personality disorders as well as cocaine-induced psychopathology in schizophrenic patients.[1]


  1. Cocaine/"crack" dependence among psychiatric inpatients. Bunt, G., Galanter, M., Lifshutz, H., Castaneda, R. The American journal of psychiatry. (1990) [Pubmed]
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