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MeSH Review

Psychopathology

 
 
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Disease relevance of Psychopathology

 

Psychiatry related information on Psychopathology

 

High impact information on Psychopathology

  • AVP also has facilitatory effects on cognitive function in humans, and marked deficits in AVP function have been associated with certain types of psychopathology [11].
  • OBJECTIVE: To test a priori hypotheses that olanzapine-treated patients have less change over time in whole brain gray matter volumes and lateral ventricle volumes than haloperidol-treated patients and that gray matter and lateral ventricle volume changes are associated with changes in psychopathology and neurocognition [12].
  • METHODS: Probands included 268 adolescents with a history of MDD, 110 adolescents with a history of nonmood disorders but no history of MDD through age 18 years, and 291 adolescents with no history of psychopathology through age 18 years [13].
  • BACKGROUND: As children with velocardiofacial syndrome (VCFS) develop, they are at increased risk for psychopathology; one third will eventually develop schizophrenia [14].
  • Homosexuality, psychopathology, and suicidality [15].
 

Chemical compound and disease context of Psychopathology

 

Biological context of Psychopathology

 

Anatomical context of Psychopathology

 

Gene context of Psychopathology

  • Catechol-O-methyltransferase (COMT) is one of the major mammalian enzymes involved in the metabolic degradation of catecholamines and is considered a candidate for several psychiatric disorders and symptoms, including the psychopathology associated with the 22q11 microdeletion syndrome [30].
  • The presence of high concentrations of both cholecystokinin and opioids in the striatum also suggests that these peptides not only may influence dopaminergic transmission, but that they may also be relevant to the psychopathology of schizophrenia and to the therapeutic effects of neuroleptics [31].
  • With regard to psychopathology, negative symptomatology appears to be the predicting factor for the absolute S100B concentration [32].
  • Elevated interleukin-2, interleukin-6 and interleukin-8 serum levels in neuroleptic-free schizophrenia: association with psychopathology [33].
  • Hence, an exaggerated cortisol response in the combined DEX/CRH test predicts the recurrence of depressive psychopathology [34].
 

Analytical, diagnostic and therapeutic context of Psychopathology

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