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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Subdural hematoma presenting as headache in systemic lupus erythematosus.

Systemic lupus erythematosus ( SLE) affects the nervous system in 75% of cases (1). A female with several neurological manifestations in the case history presented with severe headache, psychiatric disturbances, and increasing paraparesis. She was found to have bilateral subdural hematomas, and after evacuation her neuropsychiatric symptoms, including headache, disappeared. It is speculated that the reported low incidence of subdural hematomas in SLE may be more apparent than real. On the basis of our case, we recommend repeated neuroradiological investigations to uncover this important, treatable and otherwise potentially fatal cause of headache.[1]


  1. Subdural hematoma presenting as headache in systemic lupus erythematosus. Bovim, G., Jørstad, S., Schrader, H. Cephalalgia : an international journal of headache. (1990) [Pubmed]
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