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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Effects of melatonin implants on plasma concentrations of testosterone, thyroxine and prolactin in the male silver fox (Vulpes vulpes).

Melatonin administration in the form of slow-release implants advanced breeding activity in silver fox males when treatment began in June. Plasma testosterone concentrations were significantly higher in treated animals than in controls from September to November, whereas in February and March they were significantly lower. Plasma prolactin concentrations were significantly reduced immediately following melatonin treatment in June but increased to greater levels than control values and 'peaked' after 7 months. This 'peak' was associated with a rapid decrease in testosterone secretion. The normal seasonal spring rise in prolactin secretion was prevented by melatonin administration. Thyroxine values decreased and were significantly lower after 2 months of melatonin treatment.[1]

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