The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

About

Terms

 

 
 
 
 

Quantification of extracorporeal platelet deposition in cardiopulmonary bypass: effects of ZK 36374, a prostacyclin analogue.

The degree of extracorporeal platelet sequestration in 32 patients undergoing cardiopulmonary bypass has been assessed using 111In labelled platelets and both a shadow shield whole body monitor and a standard gamma camera. The effects of ZK 36374, a prostacyclin analogue, on deposition of platelets in the oxygenator and atrial line filter were also investigated. Total platelet deposition in the placebo group ranged from 2.2% to 31.7%, mean 13.9 +/- 7.8%; n = 15, and was significantly higher than the deposition in the treatment group, range 0.7% to 9.4%, mean 3.9 +/- 2.6%; n = 16, P less than 0.001. There was also a highly significant correlation between the gamma camera and whole body monitor measurements, r = 0.99, P less than 0.001, with no systematic difference between the techniques. This study demonstrates that accurate quantitative assessment of platelet deposition can be achieved with either the gamma camera or whole body monitor. In addition, significant reduction in platelet sequestration in the extracorporeal circuit can be achieved by using ZK 36374 during the bypass operation.[1]

References

  1. Quantification of extracorporeal platelet deposition in cardiopulmonary bypass: effects of ZK 36374, a prostacyclin analogue. Martin, W., Spyt, T., Thomas, I., Davidson, J.F., Wheatley, D.J. European journal of nuclear medicine. (1989) [Pubmed]
Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities