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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Localization of the human type 5, tartrate-resistant acid phosphatase gene by in situ hybridization.

We report the localization of the gene for the human type 5, tartrate-resistant, iron-containing acid phosphatase isoenzyme (HGM designation ACP5) to chromosome 15 (15q22-q26) using the technique of in situ hybridization to metaphase chromosomes. We have localized this gene using peripheral blood chromosomes obtained from both a normal male and an individual carrying an unbalanced translocation involving chromosome 15 [45,XY,-15,-18,+der(18)-t(15;18)(q13;p11)]. In addition, we have demonstrated the utility of employing a standard fluorescent staining technique (distamycin/DAPI) to an emulsion-coated, Wright-stained, and destained chromosome preparation.[1]

References

  1. Localization of the human type 5, tartrate-resistant acid phosphatase gene by in situ hybridization. Allen, B.S., Ketcham, C.M., Roberts, R.M., Nick, H.S., Ostrer, H. Genomics (1989) [Pubmed]
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