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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Metaphase

 
 
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Disease relevance of Metaphase

 

High impact information on Metaphase

 

Chemical compound and disease context of Metaphase

 

Biological context of Metaphase

 

Anatomical context of Metaphase

  • Neuroblasts in Drosophila larvae homozygous for a null mutation in the awd gene are arrested in metaphase, indicating that microtubule-associated Awd/NDP kinase plays a critical role in spindle microtubule polymerization [21].
  • Normal primary cells and tumour cell lines that express wild-type chfr exhibited delayed entry into metaphase when centrosome separation was inhibited by mitotic stress [22].
  • In vertebrates, unfertilized eggs are arrested at second meiotic metaphase by a cytostatic factor (CSF), an essential component of which is the product of the c-mos proto-oncogene [23].
  • Lymphocytes from respective patients were cultured, exposed to the clastogen bleomycin, arrested during metaphase, and examined quantitatively for chromosome breakage [24].
  • A later requirement for actin metaphase furrows in preventing the nucleation of mitotic spindles between inappropriate centrosomes is observed [25].
 

Associations of Metaphase with chemical compounds

 

Gene context of Metaphase

 

Analytical, diagnostic and therapeutic context of Metaphase

References

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