The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

About

Terms

 

 
 
 
 

Endothelin-1-induced contractions of vascular and tracheal smooth muscle: effects of nicardipine and BRL 34915.

Endothelin-1 (ET-1) produced concentration-dependent contractions of rat aorta and rat trachea. These contractions were dependent on the presence of extracellular calcium but unaffected by nicardipine. Contractions of aorta could be attenuated with the potassium channel activator BRL 34915. BRL 34915 also elicited dose-related relaxations of rat aorta and trachea precontracted with ET-1. We conclude that although the increase in calcium permeability elicited by ET-1 may not involve dihydropyridine-sensitive calcium channels, its reversal by BRL 34915 suggests that smooth muscle contraction by ET-1 may involve a voltage-linked mechanism.[1]

References

  1. Endothelin-1-induced contractions of vascular and tracheal smooth muscle: effects of nicardipine and BRL 34915. Turner, N.C., Dollery, C.T., Williams, A.J. J. Cardiovasc. Pharmacol. (1989) [Pubmed]
Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities