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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Calcium phosphate-mediated transfection alters metallothionein gene expression in response to Cd2+ and Zn2+.

The level of expression of a transfected metallothionein (MT)-IGcat fusion gene in response to cadmium differed from that of the endogenous MT-IG gene. Atomic absorption analysis indicated that the total cellular content of cadmium and zinc increased upon calcium phosphate-mediated transfection. Thus, changes in the influx/efflux of metals may regulate the level of MT gene expression.[1]


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