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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Plasma somatostatin activity in medullary cancer of the thyroid.

In a group consisting of 50 adults and 5 children with diagnosed or suspected medullary cancer of the thyroid, plasma somatostatin levels were measured in 77 samples with a sensitive radioimmunoassay. Only 2 patients had clearly enhanced plasma somatostatin immunoreactivity, both with highly active aggressive tumors. Other patients had plasma somatostatin levels of under 20 ng/l or undetectable ones. No evidence of response of somatostatin levels to pentagastrin stimulation was found.[1]


  1. Plasma somatostatin activity in medullary cancer of the thyroid. Neradilová, M., Nĕmec, J., Zamrazil, V., Bednár, J., Pechová, M., Soutorová, M. Oncology (1989) [Pubmed]
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