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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Molecular cloning and chromosomal assignment of a human perforin (PFP) gene.

Human perforin cDNA was isolated and the complete nucleotide sequence of the gene determined. The deduced amino acid sequence of human perforin showed 68.4% similarity to that of mouse perforin. RNA blot analysis of the human perforin gene revealed that the gene product is expressed preferentially in killer-type cells among cell lines tested, and in large granular lymphocytes among the peripheral blood mononuclear cells. In situ hybridization analysis with a human perforin cDNA probe revealed that the human perforin (PFP) gene is located on chromosome 17q11-21.[1]

References

  1. Molecular cloning and chromosomal assignment of a human perforin (PFP) gene. Shinkai, Y., Yoshida, M.C., Maeda, K., Kobata, T., Maruyama, K., Yodoi, J., Yagita, H., Okumura, K. Immunogenetics (1989) [Pubmed]
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