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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Myotonic dystrophy is closely linked to the gene for muscle-type creatine kinase (CKMM).

We have studied genetic linkage between the gene for creatine kinase muscle type (CKMM) and the gene for myotonic dystrophy ( DM). In a panel of 65 myotonic dystrophy families from Canada and the Netherlands, a maximum lod score (Zmax) of 22.8 at a recombination frequency (theta) of 0.03 was obtained. Tight linkage was also demonstrated for CKMM and the gene for apolipoprotein C2 (ApoC2). This establishes CKMM as a useful marker for myotonic dystrophy.[1]

References

  1. Myotonic dystrophy is closely linked to the gene for muscle-type creatine kinase (CKMM). Brunner, H.G., Korneluk, R.G., Coerwinkel-Driessen, M., MacKenzie, A., Smeets, H., Lambermon, H.M., van Oost, B.A., Wieringa, B., Ropers, H.H. Hum. Genet. (1989) [Pubmed]
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