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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Neutron brachytherapy is better than conventional radiotherapy in advanced cervical cancer.

Californium-252 (252Cf), a fast-neutron emitting radioisotope, was used for neutron brachytherapy (NT) of 82 patients with advanced (stage III and IV) cervical cancer. The results were compared with caesium-137 brachytherapy; both isotopes were given in combination with high-dose fractionated pelvic radiotherapy. In patients with stage IIIB disease (ie, tumour to the pelvic side-wall), 252Cf intracavitary therapy resulted in 54% 5-year survival compared with 12% in the caesium group. To be effective, Cf-NT must be given before external beam (photon) therapy.[1]

References

  1. Neutron brachytherapy is better than conventional radiotherapy in advanced cervical cancer. Maruyama, Y., Kryscio, R., van Nagell, J.R., Yoneda, J., Donaldson, E., Hanson, M., Beach, J.L., Feola, J.M., Martin, A., Parker, C. Lancet (1985) [Pubmed]
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