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Chemical Compound Review

CESIUM     cesium

Synonyms: Caesium, Zaesium, cesio, Cesium-133, AG-E-06587, ...
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Disease relevance of cesium


Psychiatry related information on cesium

  • Caesium levels in manic depressive psychosis [4].
  • Information on caesium retention in lynx and better estimates of deposition densities in lynxes' home ranges are important for further elucidation of factors influencing (137)Cs contamination in lynxes [5].
  • It can therefore not yet be decided whether the changes in the blood caesium levels in the patients are due to a decrease in renal excretion or are only a secondary effect of unnoticed changes in dietary habits [6].

High impact information on cesium

  • The effect of an infusion of natural motilin on the rate of gastric emptying of a standard breakfast was studied in 5 subjects using Caesium 129-tagged resin particles [7].
  • 6. SDS-PAGE and silver staining of lysates of SCV and LCV purified by caesium chloride-equilibrium density centrifugation revealed a number of proteins unique to each cell type [8].
  • In yeast cells, of which the intracellular potassium had been partly replaced by rubidium or caesium, the intracellular ion distribution was studied by means of energy-dispersive X-ray microanalysis [9].
  • The locations and numbers of potassium binding sites also differ considerably from the locations and numbers of caesium binding sites in the other structure [10].
  • Csi52, a caesium-insensitive mutant of Arabidopsis thaliana which is defective in potassium transport, is further characterized here using conventional electrophysiology, patch-clamp and radiometric approaches to identify the nature of the potassium transport lesion [11].

Chemical compound and disease context of cesium


Biological context of cesium

  • The caesium ions are distributed equally between the narrow and wide grooves of B DNA and are located close to the dyad axes lying between the planes of adjacent base-pairs [1].
  • 8. Baclofen did not reduce the duration of action potentials that were prolonged with intracellular injections of caesium ions or by superfusions with medium that contained 10 mM-tetraethylammonium (TEA).(ABSTRACT TRUNCATED AT 400 WORDS)[16]
  • Extracellular caesium ions were used to linearize the membrane properties of PCs near the resting potential [17].
  • 6. The infusion of caesium resulted in a depression of the glomerular filtration rate (G.F.R.) which was not observed when the other alkali ions were infused [18].
  • Highly repeated, or satellite, DNA fractions have been isolated from total Triturus cristatus carnifex DNA by renaturation kinetics, caesium salt centrifugation and restriction endonuclease digestion [19].

Anatomical context of cesium

  • Cesium-133 NMR studies have been carried out on suspended human erythrocytes and on perfused rat hearts in media containing CsCl [20].
  • 4. L-type Ca2+ current (ICa(L)) measured in caesium-loaded myocytes (35 C) from male and female rats of 3, 6 and 9 months of age exhibited similar characteristics [21].
  • The voltage-dependent block of ATP-sensitive potassium channels of frog skeletal muscle by caesium and barium ions [22].
  • Current-voltage relations have been measured for the fluxes of caesium ions through pores formed by gramicidin in lipid bilayer membranes [23].
  • Their diastolic depolarisation (ranging from -60 to -35 mV) was not affected by concentrations of Cs which strongly depressed the diastolic depolarisation of the B cells, even when they were hyperpolarised in the same range of potentials [24].

Associations of cesium with other chemical compounds


Gene context of cesium


Analytical, diagnostic and therapeutic context of cesium


  1. Structure of the B DNA cationic shell as revealed by an X-ray diffraction study of CsDNA. Sequence-specific cationic stabilization of B form DNA. Bartenev, V.N., Golovamov EuI, n.u.l.l., Kapitonova, K.A., Mokulskii, M.A., Volkova, L.I., Skuratovskii IYa, n.u.l.l. J. Mol. Biol. (1983) [Pubmed]
  2. The effects of vagal stimulation and applied acetylcholine on the sinus venosus of the toad. Bywater, R.A., Campbell, G., Edwards, F.R., Hirst, G.D., O'Shea, J.E. J. Physiol. (Lond.) (1989) [Pubmed]
  3. Cardiovascular and metabolic effects of caesium chloride injection in dogs--limitations as a model for the long QT syndrome. Nayebpour, M., Solymoss, B.C., Nattel, S. Cardiovasc. Res. (1989) [Pubmed]
  4. Caesium levels in manic depressive psychosis. Kumar, R., Wright, I., Naylor, G.J., Ward, N. Journal of affective disorders. (1989) [Pubmed]
  5. Concentrations of 137Cs in lynx (Lynx lynx) in relation to prey choice. Skuterud, L., Gaare, E., Kvam, T., Hove, K., Steinnes, E. Journal of environmental radioactivity. (2005) [Pubmed]
  6. The influence of renal insufficiency on caesium metabolism in man and rat (with a note on the Cs content of some biological standard materials). Gawlik, D., Behne, D., Kraft, D., Offermann, G. Journal of trace elements and electrolytes in health and disease. (1989) [Pubmed]
  7. Effect of motilin on the rate of gastric emptying and gut hormone release during breakfast. Christofides, N.D., Modlin, I.M., Fitzpatrick, M.L., Bloom, S.R. Gastroenterology (1979) [Pubmed]
  8. Developmentally regulated synthesis of an unusually small, basic peptide by Coxiella burnetii. Heinzen, R.A., Howe, D., Mallavia, L.P., Rockey, D.D., Hackstadt, T. Mol. Microbiol. (1996) [Pubmed]
  9. Subcellular localization of diffusible ions in the yeast Saccharomyces cerevisiae: quantitative microprobe analysis of thin freeze-dried sections. Roomans, G.M., Sevéus, L.A. J. Cell. Sci. (1976) [Pubmed]
  10. Crystal structure of the gramicidin/potassium thiocyanate complex. Doyle, D.A., Wallace, B.A. J. Mol. Biol. (1997) [Pubmed]
  11. Characterization of csi52, a Cs+ resistant mutant of Arabidopsis thaliana altered in K+ transport. Maathuis, F.J., Sanders, D. Plant J. (1996) [Pubmed]
  12. Nicorandil suppresses early afterdepolarisation and ventricular arrhythmias induced by caesium chloride in rabbits in vivo. Takahashi, N., Ito, M., Saikawa, T., Arita, M. Cardiovasc. Res. (1991) [Pubmed]
  13. Further studies of alinidine induced bradycardia in the presence of caesium. Dennis, P.D., Williams, E.M. Cardiovasc. Res. (1986) [Pubmed]
  14. Hepatitis B surface antigen. Role of lipids in maintaining the structural and antigenic properties of protein components. Gavilanes, F., Gomez-Gutierrez, J., Aracil, M., Gonzalez-Ros, J.M., Ferragut, J.A., Guerrero, E., Peterson, D.L. Biochem. J. (1990) [Pubmed]
  15. Potassium channel blockers quinidine and caesium halt cell proliferation in C6 glioma cells via a polyamine-dependent mechanism. Weiger, T.M., Colombatto, S., Kainz, V., Heidegger, W., Grillo, M.A., Hermann, A. Biochem. Soc. Trans. (2007) [Pubmed]
  16. Baclofen reduces post-synaptic potentials of rat cortical neurones by an action other than its hyperpolarizing action. Howe, J.R., Sutor, B., Zieglgänsberger, W. J. Physiol. (Lond.) (1987) [Pubmed]
  17. Physiology, morphology and detailed passive models of guinea-pig cerebellar Purkinje cells. Rapp, M., Segev, I., Yarom, Y. J. Physiol. (Lond.) (1994) [Pubmed]
  18. Renal function in sheep during infusion of alkali metal ions into the renal artery. Beal, A.M., Harrison, F.A. J. Physiol. (Lond.) (1975) [Pubmed]
  19. Cytological evidence of transcription of highly repeated DNA sequences during the lampbrush stage in Triturus cristatus carnifex. Varley, J.M., Macgregor, H.C., Nardi, I., Andrews, C., Erba, H.P. Chromosoma (1980) [Pubmed]
  20. Uptake of cesium ions by human erythrocytes and perfused rat heart: a cesium-133 NMR study. Davis, D.G., Murphy, E., London, R.E. Biochemistry (1988) [Pubmed]
  21. Age and gender differences in excitation-contraction coupling of the rat ventricle. Leblanc, N., Chartier, D., Gosselin, H., Rouleau, J.L. J. Physiol. (Lond.) (1998) [Pubmed]
  22. The voltage-dependent block of ATP-sensitive potassium channels of frog skeletal muscle by caesium and barium ions. Quayle, J.M., Standen, N.B., Stanfield, P.R. J. Physiol. (Lond.) (1988) [Pubmed]
  23. Gramicidin-mediated currents at very low permeant ion concentrations. Hainsworth, A.H., Hladky, S.B. Biophys. J. (1987) [Pubmed]
  24. Electrophysiological study of the two main pacemaker mechanisms in the rabbit sinus node. Kreitner, D. Cardiovasc. Res. (1985) [Pubmed]
  25. Dyskinetoplasty in two species of trypanosomatids. Hajduk, S.L. J. Cell. Sci. (1979) [Pubmed]
  26. Expression of a cloned plant K+ channel in Xenopus oocytes: analysis of macroscopic currents. Véry, A.A., Gaymard, F., Bosseux, C., Sentenac, H., Thibaud, J.B. Plant J. (1995) [Pubmed]
  27. Purification and characterization of a peanut-agglutinin-binding pancreatic-cancer-related serum mucus glycoprotein. Ching, C.K., Rhodes, J.M. Int. J. Cancer (1990) [Pubmed]
  28. Calcium-mediated inactivation of the calcium conductance in caesium-loaded giant neurones of Aplysia californica. Eckert, R., Tillotson, D.L. J. Physiol. (Lond.) (1981) [Pubmed]
  29. Di(benzothiazol-2-yl)phosphanide as a Janus-head ligand to caesium. Stey, T., Pfeiffer, M., Henn, J., Pandey, S.K., Stalke, D. Chemistry (2007) [Pubmed]
  30. Ionic permeability of, and divalent cation effects on, two ATP-gated cation channels (P2X receptors) expressed in mammalian cells. Evans, R.J., Lewis, C., Virginio, C., Lundstrom, K., Buell, G., Surprenant, A., North, R.A. J. Physiol. (Lond.) (1996) [Pubmed]
  31. Design and realization of the microwave cavity in the PTB caesium atomic fountain clock CSF1. Schröder, R., Hübner, U., Griebsch, D. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. (2002) [Pubmed]
  32. Mechanism of action of oxytocin in rat vagal neurones: induction of a sustained sodium-dependent current. Raggenbass, M., Dreifuss, J.J. J. Physiol. (Lond.) (1992) [Pubmed]
  33. Mechano-electrical transducer currents in hair cells of the cultured neonatal mouse cochlea. Kros, C.J., Rüsch, A., Richardson, G.P. Proc. Biol. Sci. (1992) [Pubmed]
  34. Substance P in the descending cholinergic projection to REM sleep-induction regions of the rat pontine reticular formation: anatomical and electrophysiological analyses. Kohlmeier, K.A., Burns, J., Reiner, P.B., Semba, K. Eur. J. Neurosci. (2002) [Pubmed]
  35. Isopycnic-centrifugation studies in caesium chloride and in caesium sulphate on dermatan sulphate proteoglycans from bovine sclera. Sheehan, J.K., Carlstedt, I., Cöster, L., Malmström, A., Fransson, L.A. Biochem. J. (1981) [Pubmed]
  36. A slow calcium-dependent chloride current in rhythmic hyperpolarization in neurones of the rabbit vesical pelvic ganglia. Nishimura, T., Akasu, T., Tokimasa, T. J. Physiol. (Lond.) (1991) [Pubmed]
  37. Effect of membrane potential on acetylcholine-induced inward current in guinea-pig ileum. Inoue, R., Isenberg, G. J. Physiol. (Lond.) (1990) [Pubmed]
  38. Pyrogallarenes as alkali metal receptors: the role of cation-pi interactions in complexation. Ahman, A., Nissinen, M. Chem. Commun. (Camb.) (2006) [Pubmed]
  39. Concurrent 5-fluorouracil, mitomycin C and irradiation in locally advanced cervix cancer. Christie, D.R., Bull, C.A., Gebski, V., Langlands, A.O. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. (1995) [Pubmed]
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