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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Analgesic properties of enkephalinase inhibitors: animal and human studies.

D-phenylalanine, bacitracin and puromycin produce long-lasting, naloxone-reversible analgesia in mice. Analgesic potency parallels potency of these compounds as inhibitors of met-enkephalin degradation by mouse brain enzymes. D-phenylalanine potentiates acupuncture analgesia in mice and humans and has been used to ameliorate a variety of human chronic pain conditions.[1]


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