Disease relevance of Acupuncture

• CONCLUSIONS: More data are needed to determine the optimal exercise regimen for treating knee osteoarthritis and to evaluate the role of topical capsaicin, laser therapy, acupuncture, transcutaneous electrical nerve stimulation, and pulsed electromagnetic fields [1].
• METHODS AND MATERIALS: Eighteen patients with xerostomia refractory to pilocarpine therapy after XRT for head and neck malignancy were offered acupuncture as palliation [2].
• Our results showed that acupuncture is as effective in relieving renal colic as Avafortan but it had a more rapid analgesic onset (3.14 +/- 2.88 minutes versus 15.44 +/- 7.55 minutes, p less than 0.05) [3].
• OBJECTIVE: To study if acupuncture, combined with ondansetron treatment, reduces nausea and vomiting associated with cyclophosphamide infusion in patients with rheumatic diseases [4].
• Five spouses among the seven couples who were positive for any of GBV-C/HGV markers had parenteral risk factors such as blood transfusion, acupuncture, and major surgery [5].

Psychiatry related information on Acupuncture

• Increase in locomotor activity was abolished by an intraperitoneal (i.p.) injection of alpha-methyl-p-tyrosine (200 mg/kg) at 2 h before insertion of acupuncture [6].
• Prospective randomized trial using laser acupuncture versus desmopressin in the treatment of nocturnal enuresis [7].
• Anecdotal studies have reported acupuncture alleviating the severity of withdrawal symptoms associated with cocaine abuse [8].
• However, patients who received the spirituality-focused group therapy in addition to their assigned acupuncture treatment were abstinent from heroin and cocaine for significantly longer, and had greater reductions in depression and anxiety than did those patients not receiving spirituality-focused psychotherapy [9].
• Select the optimum treatment for your patient by learning the efficacy and applicability of interventions such as counseling, nicotine replacement therapy, non-nicotine drugs, harm reduction, and acupuncture [10].

High impact information on Acupuncture

• Acupuncture for the treatment of cocaine addiction [11].
• Acupuncture to prevent cisplatin-associated vomiting [12].
• Acupuncture relief of chronic pain syndrome correlates with increased plasma met-enkephalin concentrations [13].
• Our data suggest that cerebellum serves as important activation loci during the acupuncture stimulation of PC6, and clinical efficacy of PC6 may be mediated by the cerebellar vestibular neuromatrix [14].
• Acupuncture and nicotine withdrawal [15].

Chemical compound and disease context of Acupuncture

• We examined the effect of acupuncture on nicotine-induced behavioral locomotor activity and c-fos expression in the nucleus accumbens and striatum utilizing the immunocytochemical detection of the Fos protein [16].
• Acupuncture versus placebo versus sumatriptan for early treatment of migraine attacks: a randomized controlled trial [17].
• Treatment with real or placebo acupuncture failed to modulate the bronchial hyperreactivity to histamine [18].
• Effects of acupuncture on vasopressin-induced emesis in conscious dogs [19].
• RESULTS: Evidence exists to support the efficacy of reducing pain from osteoarthritis (OA) for acupuncture; devil's claw, avocado/soybean unsaponifiables, Phytodolor and capsaicin; and chondroitin, glucosamine, and SAMe [20].

Biological context of Acupuncture

• Event-related potential correlates of analgesia; comparison of fentanyl, acupuncture, and nitrous oxide [21].
• The effects of electrical acupuncture delivered at 2 Hz to LI-4, the opiate fentanyl 0.1 mg i.v., and the inhalation analgesia mixture of 33% nitrous oxide in oxygen were examined in volunteers undergoing painful tooth pulp stimulation [21].
• The decreased response of heart rate following acupuncture was attenuated by administration of atropine and propranolol [22].
• Although studies of adequate design, sample size, and appropriate control on the use of acupuncture on ovulation induction are lacking, there is only one prospective randomized controlled study examining the efficacy of acupuncture in patients undergoing IVF [23].
• Effect of acupuncture on 6-hydroxydopamine-induced nigrostratal dopaminergic neuronal cell death in rats [24].

Anatomical context of Acupuncture

• Increased beta-endorphin but not met-enkephalin levels in human cerebrospinal fluid after acupuncture for recurrent pain [25].
• CONCLUSIONS: Acupuncture to the kidney-bladder distinct meridian neither relieves lower urinary tract symptoms nor impacts PSA [26].
• These findings suggest that acupuncture has an effect on the depression-like disorder caused by MS, possibly by modulating NPY expression in the hippocampus [27].
• The in vivo microdialysis study was designed to investigate the effect of acupuncture on acute ethanol-induced dopamine release in the nucleus accumbens and the potential role of the GABA(B) receptor system in acupuncture [28].
• Antipyretic effects of acupuncture on the lipopolysaccharide-induced fever and expression of interleukin-6 and interleukin-1 beta mRNAs in the hypothalamus of rats [29].

Associations of Acupuncture with chemical compounds

• Preventive effect of acupuncture on histamine-induced itch: a blinded, randomized, placebo-controlled, crossover trial [30].
• CONCLUSIONS: This study suggests that in combination with ondansetron i.v., invasive needle acupuncture at P6 compared with nonskin-penetrating placebo acupuncture has no additional effect for the prevention of acute nausea and vomiting in high-dose chemotherapy [31].
• In random order the site of the acupuncture had been previously infiltrated with normal saline solution in half of the patients and 1% lidocaine in the remaining patients [32].
• During the acupuncture period, the number of anginal attacks per week was reduced from 10.6 to 6.1 compared with placebo (P less than 0.01) [33].
• No conclusions can be derived from this study concerning the importance of choosing points and the rules of Traditional Chinese Medicine. Using the new placebo method as control for other ailments could improve the evidence of specific acupuncture effects beyond pain treatment [34].

Gene context of Acupuncture

• The results showed significant increases in the release of CGRP, NPY and VIP both during and after acupuncture stimulation, especially in connection with electro-acupuncture [35].
• There was little difference in the levels of IL-1 or IL-6 due to the treatment with acupuncture in the patients with CH, but significantly reduced plasma levels of TNF-alpha were observed [36].
• Inhibition of acid secretion by electrical acupuncture is mediated via beta-endorphin and somatostatin [37].
• LPS increased hypothalamic mRNA levels of interleukin-6 and interleukin-1 beta which, on the contrary, were also reduced to normal levels by acupuncture stimulation on BL66 [29].
• INTERVENTIONS: This study evaluated a standardized acupuncture technique vs an appropriately validated placebo/control (mock transcutaneous electrical nerve stimulation [TENS]) for disabling, nonmalignant breathlessness (largely COPD) [38].

Analytical, diagnostic and therapeutic context of Acupuncture

• PURPOSE: The purpose is to investigate an additional antiemetic effect to ondansetron with needle acupuncture at P6 compared with nonskin-penetrating placebo acupuncture in patients undergoing high-dose chemotherapy and autologous peripheral blood stem cell transplantation [31].
• High versus low intensity acupuncture analgesia for treatment of chronic pain: effects on platelet serotonin [39].
• The effect of acupuncture on patients with rheumatoid arthritis: a randomized, placebo-controlled cross-over study [40].
• These results suggest that stimulation of specific acupoints inhibits ethanol-induced dopamine release by modulating GABA(B) activity and imply that acupuncture may be effective in blocking the reinforcing effects of ethanol [28].
• Two RCTs compared adjunctive acupuncture with usual care only and reported a reduction of meperidine and/or epidural analgesia [41].

References