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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Angiotensin-converting enzyme in sarcoid and chalazion granulomas of the conjunctiva.

Angiotensin-converting enzyme (ACE) was studied immunohistochemically in conjunctival biopsies from 6 patients with systemic sarcoidosis, 4 patients with posterior non-sarcoid uveitis and in specimens from 4 patients with chalazion of the eyelid. Specimens with sarcoid granulomas showed intense ACE-positive immunoreactivity in epitheloid cells of the granuloma, whereas chalazion granulomas did not contain ACE-immunoreactivity. There was no difference in staining patterns between specimens without granulomas. Thus immunohistochemical staining for ACE may be of help in differentiating conjunctival granulomatous tissue of a chalazion from sarcoid granuloma.[1]

References

  1. Angiotensin-converting enzyme in sarcoid and chalazion granulomas of the conjunctiva. Immonen, I., Friberg, K., Grönhagen-Riska, C., von Willebrand, E., Fyhrquist, F. Acta ophthalmologica. (1986) [Pubmed]
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