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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

3'-deoxyadenosine and implantation of delayed blastocysts in mice.

Pregnant mice were ovariectomized 3 days after mating and pregnancy was maintained by progesterone treatment. Different regimens of intraperitoneal injections of 3'-deoxyadenosine were applied 3 days after ovariectomy. Repetition of the injections at 3 h intervals induced a significant rate of implantation by delayed blastocysts. Other types of treatment with 3-deoxyadenosine as well as adenosine injections were found to be ineffective. Paradoxically, 3'-deoxyadenosine treatment had an adverse effect on the overall pregnancy rate found at autopsy.[1]

References

  1. 3'-deoxyadenosine and implantation of delayed blastocysts in mice. Fernandez-Noval, A., Leroy, F. J. Endocrinol. (1979) [Pubmed]
 
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