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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Pharmacokinetics and tissue kinetics of 1 gm cefotetan prophylaxis in abdominal or vaginal hysterectomy.

Plasma and tissue levels of cefotetan after a single-gram intravenous preoperative dose were measured. Levels were high in some tissues (parametrium, fascia) but quite low in others (subcutaneous fat). The implications as to the prophylactic effectiveness of this drug are addressed.[1]

References

  1. Pharmacokinetics and tissue kinetics of 1 gm cefotetan prophylaxis in abdominal or vaginal hysterectomy. Orr, J.W., Sisson, P.F., Barrett, J.M., Ellington, J.R., Jennings, R.H., Taylor, D.L. Am. J. Obstet. Gynecol. (1988) [Pubmed]
 
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