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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Metabolism of 2-aminoethylphosphonic acid during embryonic development of the schistosomal vector Biomphalaria glabrata.

1. Egg masses of the Planorbid snail Biomphalaria glabrata contain 2-aminoethylphosphonic acid (AEP) in three different chemical environments, as determined by 31P nuclear magnetic resonance spectroscopy, giving signals at 20.9, 21.0 and 23.4 delta. 2. The signal at 21.0 delta decreased in intensity during embryonic development, whereas the other two did not change significantly. 3. The following relationship is suggested: Extraembryonic AEP--------Intraembryonic AEP--------Phosphates. 4. pH Titration behavior of macromolecularly-bound AEP and synthetic derivatives of AEP was examined and indicates that AEP is found in the egg masses linked to other molecules in the following ways: (a) R2-NH-CH2CH2-P(O)(OH)(OR1), (b) R3-NH-CH2-P(O)(OR2)(OR1), (c) NH2-CH2CH2P(O)(OH)(OR1).[1]

References

  1. Metabolism of 2-aminoethylphosphonic acid during embryonic development of the schistosomal vector Biomphalaria glabrata. Meneses, P., Glonek, T., Henderson, T.O. Comp. Biochem. Physiol., B (1987) [Pubmed]
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