Disease relevance of Biomphalaria

• Effect of ultraviolet and gamma radiations on the activities of aspartate aminotransferase (AST), alanine aminotransferase (ALT) and lactate dehydrogenase (LD) in Biomphalaria alexandrina snails, the specific intermediate host of schistosomiasis, was investigated [1].
• The aim of this study was to determine the toxicity of niclosamide (Bayluscide (R)) on Melanoides tuberculata and Biomphalaria glabrata under laboratory conditions [2].

High impact information on Biomphalaria

• Southern blot analysis, genomic polymerase chain reaction, and immunolocalization demonstrated that the trypsin-like proteases are in fact not from the schistosome, but are released with larvae from the snail host Biomphalaria glabrata [3].
• Crystal structure of a novel tetrameric complex of agonist-bound ligand-binding domain of Biomphalaria glabrata retinoid X receptor [4].
• The amino acid sequence analysis of the major squid allergen showed a marked homology with tropomyosin from blood fluke planorbid (Biomphalaria glabrata), which is a common vector snail of Schistosoma mansoni [5].
• Calcium carbonate modifications in the mineralized shell of the freshwater snail Biomphalaria glabrata [6].
• Purification and characterization of a tetrameric alpha-macroglobulin proteinase inhibitor from the gastropod mollusc Biomphalaria glabrata [7].

Chemical compound and disease context of Biomphalaria

• Effects of Bayluscide WP 70 on the survival and water-leaving behaviour of Biomphalaria straminea, snail host of schistosomiasis in northeast Brazil [8].
• Polymeric controlled release formulations of niclosamide for control of Biomphalaria alexandrina, the vector snail of schistosomiasis [9].

Biological context of Biomphalaria

• Killing of Schistosoma mansoni sporocysts by Biomphalaria glabrata hemolymph in vitro: alteration of hemocyte behavior after poly-L-lysine treatment of plastic, and the kinetics of killing by different host strains [10].
• To investigate this possibility, the host-parasite relationships of five praziquantel-resistant and five praziquantel-susceptible isolates of Schistosoma mansoni were compared in Biomphalaria glabrata snails and outbred CD(1) albino mice [11].
• Metabolism of 2-aminoethylphosphonic acid during embryonic development of the schistosomal vector Biomphalaria glabrata [12].
• Esterification of cholesterol by the hepatopancreas of the mollusc Biomphalaria glabrata [13].
• Effect of the organophosphorous insecticide, chlorpyrifos (Dursban), on growth, fecundity and mortality of Biomphalaria alexandrina and on the production of Schistosoma mansoni cercariae in the snail [14].

Anatomical context of Biomphalaria

• Cloning of a beta integrin subunit cDNA from an embryonic cell line derived from the freshwater mollusc, Biomphalaria glabrata [15].
• Effects of ammonium chloride on microbicidal activity in hemocytes of Biomphalaria glabrata (Mollusca: Pulmonata) [16].
• 4. Inhibition of the agglutinating activity of Helisoma hemolymph could be accomplished with N-Acetyl-D-Galactosamine, but this sugar had no effect on the activity of Biomphalaria agglutinins [17].
• Distinct binding patterns of fucose-specific lectins from Biomphalaria alexandrina and Lotus tetragonolobus to murine lymphocyte subsets [18].
• Junctions between Sertoli cells, which form a continuous layer at the periphery of the 'acinus' in the ovotestis of Biomphalaria glabrata (mollusc gastropod), have been studied with conventional sections, lanthanum impregnation, replicas and scanning analysis of unstained sections [19].

Associations of Biomphalaria with chemical compounds

• BamHI-digested Biomphalaria glabrata DNA contains a repetitive 2.0-kb fragment which is readily discernible by ethidium bromide staining [20].
• In order to test the hypothesis that retinoic acid signaling pathways involving RXRs are present in the Lophotrochozoa, we have sought to isolate conserved members of this family from the platyhelminth parasite Schistosoma mansoni and its intermediate host, the mollusk Biomphalaria glabrata [21].
• Evidence for a family of schistosome glycan-binding lectins in Biomphalaria alexandrina [22].
• The activity of the potassium salt of lapachol against the snail Biomphalaria glabrata and its egg masses was tested [23].
• The adenylate nucleotide pool in the digestive gland-gonad complex of Biomphalaria glabrata infected by Schistosoma mansoni [24].

Gene context of Biomphalaria

• To investigate the nature of carbohydrates that evoke a defensive response in hemocytes of the gastropod Biomphalaria glabrata, we tested eight different carbohydrates, conjugated to bovine serum albumin (BSA), for generation of reactive oxygen species (ROS) [25].
• Biomphalaria peregrina was found to be naturally infected with cercariae of Zygocotyle lunata in a pond of the Zoological Garden of Buenos Aires. Mice and chicks were fed metacercariae and gravid adults recovered [26].
• Biogenic amine metabolism in Biomphalaria glabrata I. Catechol-O-methyltransferase activity [27].
• Precipitins against the antigen of the intermediate host, Biomphalaria glabrata, were demonstrated in 66% of the sera [28].
• Immunoelectrophoretic study on common antigens of São Lourenço da Mata and Belo Horizonte strains of Schistosoma mansoni adult worms and Biomphalaria snails [29].

Analytical, diagnostic and therapeutic context of Biomphalaria

• The hemagglutinins from the spawn of the water snail Biomphalaria glabrata were isolated by affinity chromatography on hog gastric mucin coupled to Sepharose 4B [30].

References