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Disease relevance of Biomphalaria


High impact information on Biomphalaria


Chemical compound and disease context of Biomphalaria


Biological context of Biomphalaria


Anatomical context of Biomphalaria


Associations of Biomphalaria with chemical compounds

  • BamHI-digested Biomphalaria glabrata DNA contains a repetitive 2.0-kb fragment which is readily discernible by ethidium bromide staining [20].
  • In order to test the hypothesis that retinoic acid signaling pathways involving RXRs are present in the Lophotrochozoa, we have sought to isolate conserved members of this family from the platyhelminth parasite Schistosoma mansoni and its intermediate host, the mollusk Biomphalaria glabrata [21].
  • Evidence for a family of schistosome glycan-binding lectins in Biomphalaria alexandrina [22].
  • The activity of the potassium salt of lapachol against the snail Biomphalaria glabrata and its egg masses was tested [23].
  • The adenylate nucleotide pool in the digestive gland-gonad complex of Biomphalaria glabrata infected by Schistosoma mansoni [24].

Gene context of Biomphalaria

  • To investigate the nature of carbohydrates that evoke a defensive response in hemocytes of the gastropod Biomphalaria glabrata, we tested eight different carbohydrates, conjugated to bovine serum albumin (BSA), for generation of reactive oxygen species (ROS) [25].
  • Biomphalaria peregrina was found to be naturally infected with cercariae of Zygocotyle lunata in a pond of the Zoological Garden of Buenos Aires. Mice and chicks were fed metacercariae and gravid adults recovered [26].
  • Biogenic amine metabolism in Biomphalaria glabrata I. Catechol-O-methyltransferase activity [27].
  • Precipitins against the antigen of the intermediate host, Biomphalaria glabrata, were demonstrated in 66% of the sera [28].
  • Immunoelectrophoretic study on common antigens of São Lourenço da Mata and Belo Horizonte strains of Schistosoma mansoni adult worms and Biomphalaria snails [29].

Analytical, diagnostic and therapeutic context of Biomphalaria


  1. Variation of transaminases and lactate dehydrogenase in irradiated Biomphalaria alexandrina snails. Nabih, I., el-Ansary, A. Cell. Mol. Biol. (1991) [Pubmed]
  2. The molluscicidal activity of niclosamide (Bayluscide WP70(R)) on Melanoides tuberculata (Thiaridae), a snail associated with habitats of Biomphalaria glabrata (Planorbidae). Giovanelli, A., Silva, C.L., Medeiros, L., Vasconcellos, M.C. Mem. Inst. Oswaldo Cruz (2002) [Pubmed]
  3. Schistosome invasion of human skin and degradation of dermal elastin are mediated by a single serine protease. Salter, J.P., Lim, K.C., Hansell, E., Hsieh, I., McKerrow, J.H. J. Biol. Chem. (2000) [Pubmed]
  4. Crystal structure of a novel tetrameric complex of agonist-bound ligand-binding domain of Biomphalaria glabrata retinoid X receptor. de Groot, A., de Rosny, E., Juillan-Binard, C., Ferrer, J.L., Laudet, V., Pierce, R.J., Pebay-Peyroula, E., Fontecilla-Camps, J.C., Borel, F. J. Mol. Biol. (2005) [Pubmed]
  5. Identification of the first major allergen of a squid (Todarodes pacificus). Miyazawa, H., Fukamachi, H., Inagaki, Y., Reese, G., Daul, C.B., Lehrer, S.B., Inouye, S., Sakaguchi, M. J. Allergy Clin. Immunol. (1996) [Pubmed]
  6. Calcium carbonate modifications in the mineralized shell of the freshwater snail Biomphalaria glabrata. Hasse, B., Ehrenberg, H., Marxen, J.C., Becker, W., Epple, M. Chemistry (Weinheim an der Bergstrasse, Germany) (2000) [Pubmed]
  7. Purification and characterization of a tetrameric alpha-macroglobulin proteinase inhibitor from the gastropod mollusc Biomphalaria glabrata. Bender, R.C., Bayne, C.J. Biochem. J. (1996) [Pubmed]
  8. Effects of Bayluscide WP 70 on the survival and water-leaving behaviour of Biomphalaria straminea, snail host of schistosomiasis in northeast Brazil. Sarquis, O., Pieri, O.S., dos Santos, J.A. Mem. Inst. Oswaldo Cruz (1997) [Pubmed]
  9. Polymeric controlled release formulations of niclosamide for control of Biomphalaria alexandrina, the vector snail of schistosomiasis. Kenawy, e.l.-.R., Rizk, e.l.-.S. Macromolecular bioscience. (2004) [Pubmed]
  10. Killing of Schistosoma mansoni sporocysts by Biomphalaria glabrata hemolymph in vitro: alteration of hemocyte behavior after poly-L-lysine treatment of plastic, and the kinetics of killing by different host strains. Boehmler, A.M., Fryer, S.E., Bayne, C.J. J. Parasitol. (1996) [Pubmed]
  11. Biological characteristics of praziquantel-resistant and -susceptible isolates of Schistosoma mansoni. Liang, Y.S., Coles, G.C., Dai, J.R., Zhu, Y.C., Doenhoff, M.J. Ann. Trop. Med. Parasitol. (2001) [Pubmed]
  12. Metabolism of 2-aminoethylphosphonic acid during embryonic development of the schistosomal vector Biomphalaria glabrata. Meneses, P., Glonek, T., Henderson, T.O. Comp. Biochem. Physiol., B (1987) [Pubmed]
  13. Esterification of cholesterol by the hepatopancreas of the mollusc Biomphalaria glabrata. De Souza, A.M., De Oliveira, D.N. An. Acad. Bras. Cienc. (1975) [Pubmed]
  14. Effect of the organophosphorous insecticide, chlorpyrifos (Dursban), on growth, fecundity and mortality of Biomphalaria alexandrina and on the production of Schistosoma mansoni cercariae in the snail. Ibrahim, W.L., Furu, P., Ibrahim, A.M., Christensen, N.O. J. Helminthol. (1992) [Pubmed]
  15. Cloning of a beta integrin subunit cDNA from an embryonic cell line derived from the freshwater mollusc, Biomphalaria glabrata. Davids, B.J., Wu, X.J., Yoshino, T.P. Gene (1999) [Pubmed]
  16. Effects of ammonium chloride on microbicidal activity in hemocytes of Biomphalaria glabrata (Mollusca: Pulmonata). Douglas, J.S., Sullivan, J.T. Dev. Comp. Immunol. (1992) [Pubmed]
  17. Agglutinins and lysins in the molluscan family Planorbidae: a survey of hemolymph, egg-masses, and albumen-gland extracts. Michelson, E.H., Dubois, L. Biol. Bull. (1977) [Pubmed]
  18. Distinct binding patterns of fucose-specific lectins from Biomphalaria alexandrina and Lotus tetragonolobus to murine lymphocyte subsets. Mansour, M.H., Abdul-Salam, F., Al-Shemary, T. Immunobiology (2005) [Pubmed]
  19. Structure and possible functional role of septate junctions in the ovotestis of a pond snail: inter-Sertoli junctions. Anelli, G., Franchi, E., Camatini, M. J. Submicrosc. Cytol. (1985) [Pubmed]
  20. Identification of a repetitive element in the snail Biomphalaria glabrata: relationship to the reverse transcriptase-encoding sequence in LINE-1 transposons. Knight, M., Miller, A., Raghavan, N., Richards, C., Lewis, F. Gene (1992) [Pubmed]
  21. A conserved retinoid X receptor (RXR) from the mollusk Biomphalaria glabrata transactivates transcription in the presence of retinoids. Bouton, D., Escriva, H., de Mendonça, R.L., Glineur, C., Bertin, B., Noël, C., Robinson-Rechavi, M., de Groot, A., Cornette, J., Laudet, V., Pierce, R.J. J. Mol. Endocrinol. (2005) [Pubmed]
  22. Evidence for a family of schistosome glycan-binding lectins in Biomphalaria alexandrina. Mansour, M.H. Dev. Comp. Immunol. (1995) [Pubmed]
  23. Molluscicidal and trypanocidal activities of lapachol derivatives. Santos, A.F., Ferraz, P.A., de Abreu, F.C., Chiari, E., Goulart, M.O., Sant'Ana, A.E. Planta Med. (2001) [Pubmed]
  24. The adenylate nucleotide pool in the digestive gland-gonad complex of Biomphalaria glabrata infected by Schistosoma mansoni. Thompson, S.N., Yamada, K.A. Mol. Biochem. Parasitol. (1984) [Pubmed]
  25. Production of reactive oxygen species by hemocytes of Biomphalaria glabrata: carbohydrate-specific stimulation. Hahn, U.K., Bender, R.C., Bayne, C.J. Dev. Comp. Immunol. (2000) [Pubmed]
  26. New intermediate hosts in the life cycle of Zygocotyle lunata in South America. Ostrowski de Núñez, M., Spatz, L., González Cappa, S.M. J. Parasitol. (2003) [Pubmed]
  27. Biogenic amine metabolism in Biomphalaria glabrata I. Catechol-O-methyltransferase activity. Guchhait, R.B., Bourgeois, J.G., Bueding, E. Int. J. Neurosci. (1980) [Pubmed]
  28. Immunodiagnosis of human schistosomiasis using different immunoprecipitation techniques. Deelder, A.M., Kornelis, D., Rier, W.B., Ten-Jet-Foei, C.L. Zeitschrift für Parasitenkunde (Berlin, Germany) (1975) [Pubmed]
  29. Immunoelectrophoretic study on common antigens of São Lourenço da Mata and Belo Horizonte strains of Schistosoma mansoni adult worms and Biomphalaria snails. de Santana, J.V., Iwanaga, Y., Telles, A.M., da Silva, M.R., Gonçalves, J.F., Tateno, S. Rev. Inst. Med. Trop. Sao Paulo (1992) [Pubmed]
  30. Isolation and characterization of a lectin from the snail Biomphalaria glabrata and a study of its combining site. Bretting, H., Stanislawski, E., Jacobs, G., Becker, W. Biochim. Biophys. Acta (1983) [Pubmed]
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