Role of arginine vasopressin in regulation of systemic arterial pressure.
Arginine vasopressin ( AVP) not only influences renal water metabolism but also has profound cardiovascular effects. Physiologic levels of the hormone produce a pressor response in the basal state when vasoregulatory reflex mechanisms are interrupted. During hypovolemia, vasopressin affects systemic blood pressure independent of the renin-angiotensin system and efferent sympathetic pathways. Many studies implicate AVP in the pathogenesis of hypertension, but the actual mechanism and relative importance of vasopressin's role remain a matter of intense investigation.[1]References
- Role of arginine vasopressin in regulation of systemic arterial pressure. Rossi, N.F., Schrier, R.W. Annu. Rev. Med. (1986) [Pubmed]
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