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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

False-positive cryptococcal antigen test and cervical prevertebral abscess.

A false-positive latex agglutination test for cryptococcal antigen occurred in a patient with a cervical prevertebral abscess and vertebral osteomyelitis caused by Klebsiella pneumoniae. Using a commercial latex agglutination test kit, a cryptococcal antigen titer of 1:32 was found in the CSF, but no cryptococcal antigen was found when the CSF was retested at a reference laboratory. The false-positive test resulted in unnecessary therapy with amphotericin B and delay in appropriate diagnostic studies and therapy.[1]

References

  1. False-positive cryptococcal antigen test and cervical prevertebral abscess. MacKinnon, S., Kane, J.G., Parker, R.H. JAMA (1978) [Pubmed]
 
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