Auditory evoked potentials and response to lithium prophylaxis.
Auditory evoked potentials were recorded in 28 euthymic patients with affective psychosis who had received lithium prophylaxis for at least 5 years. Binaural clicks at 4 intensities were presented in randomized order via headphones. Potentials were recorded from Cz, C3, and C4 referenced to linked mastoid electrodes. N1-P2 amplitudes, N1 and P2 latencies, and the slope of the amplitude/stimulus intensity function (ASF) were determined in each patient. The patients were divided into responders and nonresponders on the basis of whether or not they had been hospitalized for treatment of relapses during the last 5 years of lithium prophylaxis. The ASF was steeper for all leads in responders than in nonresponders. In addition, N1 latencies were shorter for all leads in responders than in nonresponders. Age played a role in the differences observed between responders and nonresponders for ASF, but not for N1 latencies.[1]References
- Auditory evoked potentials and response to lithium prophylaxis. Hegerl, U., Ulrich, G., Müller-Oerlinghausen, B. Pharmacopsychiatry (1987) [Pubmed]
Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
