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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Ultrastructural changes in the cerebellum of nursling rats given corynetoxin, the aetiological agent of annual ryegrass toxicity.

Nursling rats were given a lethal dose of corynetoxin and the sequential morphological alterations in the cerebellum were examined at daily intervals up to 3 days post-inoculation. Ultrastructural changes were those of cerebral vascular damage, which was usually focal in affected endothelial cells, and resulted in vascular stasis or thrombosis. These changes ultimately constituted a failure of perfusion in focal areas of brain parenchyma supplied by these vessels, resulting in necrosis.[1]

References

  1. Ultrastructural changes in the cerebellum of nursling rats given corynetoxin, the aetiological agent of annual ryegrass toxicity. Finnie, J.W., Mukherjee, T.M. J. Comp. Pathol. (1986) [Pubmed]
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