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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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In vitro activity of Ro 15-8074, a new oral cephalosporin, against Neisseria gonorrhoeae.

Ro 15-8074, a new cephalosporin the pivaloyloxymethylester of which (Ro 15-8075) is orally absorbable, showed greater in vitro activity than cefaclor against 48 Neisseria gonorrhoeae strains, including 25 penicillinase-producing strains. Unlike cefaclor, Ro 15-8074 was unaffected by increase in inoculum size, and it exhibited a remarkable stability against gonococcal beta-lactamase hydrolysis.[1]

References

  1. In vitro activity of Ro 15-8074, a new oral cephalosporin, against Neisseria gonorrhoeae. Ng, W.S., Chau, P.Y., Leung, Y.K., Wong, P.C. Antimicrob. Agents Chemother. (1985) [Pubmed]
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