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O'Keefe, J.C. et al.

Ventricular arrhythmias complicating weight reduction therapy in a patient with a prolonged QT interval.

Serious ventricular arrhythmias are known to occur in patients with long QT intervals. We describe a case of torsade de pointes occurring in a patient with a prolonged QT interval while taking a 1000 calorie diet, diethylpropion hydrochloride (Tenuate Dospan) and bendrofluazide. In patients with long QT intervals, hypokalaemia and drugs which further delay repolarization may facilitate the development of life threatening arrhythmias.[1]

References

Ventricular arrhythmias complicating weight reduction therapy in a patient with a prolonged QT interval. O'Keefe, J.C., Butrous, G.S., Dymond, D.S., Littlejohns, P., Peters, N., Banim, S.O. Postgraduate medical journal. (1985) [Pubmed]

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