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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Aztreonam plus clindamycin as therapy for pelvic infections in women.

Aztreonam, a new monobactam antibiotic with specific gram-negative aerobic activity, was used in combination with clindamycin in the treatment of 40 women with pelvic infection, including post-partum endometritis, pelvic inflammatory disease, and post-hysterectomy pelvic cellulitis. Clinical cure was achieved in 87 percent of patients. Failure was related to the limited gram-positive aerobic spectrum of clindamycin. All aerobic gram-negative enteric organisms were sensitive in vitro to less than 0.125 microgram/ml of aztreonam.[1]


  1. Aztreonam plus clindamycin as therapy for pelvic infections in women. Pastorek, J.G., Cole, C., Aldridge, K.E., Crapanzano, J.C. Am. J. Med. (1985) [Pubmed]
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