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S-antigen is coded by [poly A+] mRNA from bovine retina.

Total RNA, [poly (A)-] mRNA and [poly (A)+] mRNA purified from bovine retina were translated in vitro in a rabbit reticulocyte lysate system. Immunoprecipitation of translation products with antibodies to the retinal S-antigen (a photoreceptor specific protein involved in autoimmune retinal disease) revealed this protein as a 50,000 daltons band comigrating with purified S-antigen. This indicates that the S-antigen is synthesized in the retina and is not a maturation or degradation product of a larger protein. Its messenger RNA is the polyadenylated RNA, as for some other proteins expressed in nervous tissue.[1]

References

  1. S-antigen is coded by [poly A+] mRNA from bovine retina. Altério, J., Dorey, C., Mirshahi, M., Faure, J.P., Barritault, D. Biochem. Biophys. Res. Commun. (1985) [Pubmed]
 
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