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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Plasmenylethanolamine: growth factor for cholesterol-reducing Eubacterium.

A plasmalogen, plasmenylethanolamine, is required for in vitro growth of strains of Eubacterium which convert cholesterol to coprostanol. Plasmenylethanolamine was isolated from calf brain by selective saponification of lipid fractions separated by thin-layer or column chromatography. Cholesterol-containing thioglycolate broth plus purified plasmenylethanolamine or its 2-lyso derivative supported growth of Eubacterium ATCC 21408 and a cholesterol-reducing Eubacterium isolated from baboon feces. Plasmenylethanolamine obtained from commercial sources also supported growth of these organisms, but none of a number of other pure lipids would support growth. Metabolism of the alkenyl ether group of plasmenylethanolamine occurred during growth.[1]


  1. Plasmenylethanolamine: growth factor for cholesterol-reducing Eubacterium. Mott, G.E., Brinkley, A.W. J. Bacteriol. (1979) [Pubmed]
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