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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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The analgesic action of some flavonoids in the hot plate test.

Albino-Swiss male mice were tested in the hot plate test. Oligomeric procyjanidin (OL-1), rutin, quercetin, hyperoside and vitexin rhamnoside were administered intraperitoneally in doses 3.5 and 10 mg/kg. It was found that OL-1, rutin and hyperoside but not vitexin rhamnoside exert analgesic action, whereas quercetin even decreases the pain threshold level. The mechanism of the analgesic action of flavonoids remains to be explained.[1]

References

  1. The analgesic action of some flavonoids in the hot plate test. Rylski, M., Duriasz-Rowińska, H., Rewerski, W. Acta physiologica Polonica. (1979) [Pubmed]
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