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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Diphtheria carriers in Manchester: simultaneous infection with toxigenic and non-toxigenic mitis strains.

A toxigenic strain of Corynebacterium diphtheriae mitis was isolated from a 10-week-old baby with membranous tonsillitis, and over the next 6 months thirty-nine symptom-free carriers of nitrate-positive mitis strains were found. All carriers were cleared by 14 days' treatment with erythromycin, though several relapsed after a 5-day course. Four contacts carried both toxigenic and non-toxigenic mitis strains; epidemiological evidence and phage studies suggest that these had a common origin. These findings have implications for the epidemiology of diphtheria and for the routine testing of isolates for toxigenicity.[1]

References

  1. Diphtheria carriers in Manchester: simultaneous infection with toxigenic and non-toxigenic mitis strains. Simmons, L.E., Abbott, J.D., Macaulay, M.E., Jones, A.E., Ironside, A.G., Mandal, B.K., Stanbridge, T.N., Maximescu, P. Lancet (1980) [Pubmed]
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