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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Influence of dimercaprol (2,3-dimercapto-1-propanol) on the pharmacokinetics of 111In-bleomycin in the P-1798 lymphoma-bearing BALB/c mouse.

The pharmacokinetics of 111 indium-labeled bleomycin were altered in the P-1798 tumor-bearing BALB/c mouse when pretreated with the dithiol 2,3-dimercapto-1-propanol ( Bal). 1 mg of BAL administered 1 h prior to 20 microCi of 111In-bleomycin resulted in 2:1 tumor loading and 3:1 liver loading of 111In-bleomycin over controls (p less than or equal to 0.05 at the 2- to 3-hour interval). Muscle uptake during this interval remained at unity.[1]

References

  1. Influence of dimercaprol (2,3-dimercapto-1-propanol) on the pharmacokinetics of 111In-bleomycin in the P-1798 lymphoma-bearing BALB/c mouse. Sartiano, G.P., Levine, G., Boggs, S.S. Oncology (1980) [Pubmed]
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