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Chemical Compound Review

INDIUM     indium

Synonyms: indio, AC1NSEAS, indium(1+), AG-G-95782, ACMC-20akqo, ...
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Disease relevance of indium


High impact information on indium


Chemical compound and disease context of indium


Biological context of indium

  • Application of a similar electrical potential to cells cultured on indium tin oxide surfaces had no effect on cell shape or function [14].
  • Microvascular permeability was quantitatively assessed as a protein leak index by measuring the rate of extravascular accumulation of radiolabeled protein (indium 113m transferrin) normalized for vascular surface area (technetium 99m erythrocytes) [15].
  • Since indium, a similar class 3A metal, has not been well studied, we examined its effects on cellular iron uptake and cellular proliferation [16].
  • Therefore, modification of the gold particle surface by indium has been used to vary the active site characteristics of a suitable catalyst, and a selective decoration of gold particle faces has been observed, leaving edges free [17].
  • Indium 111-labeled monoclonal antibody to cardiac myosin was examined for efficacy in the detection of cardiac graft rejection and rejection-related myocyte necrosis [18].

Anatomical context of indium

  • An 8-ml bolus containing 50 mu Ci of indium 111-diethylene triamine pentaacetic acid was instilled into the cecum via a 2-mm tube, which was passed orally, and serial scintigrams were obtained over 48 h [19].
  • In this report a scintigraphic technique using 2,6-dimethylphenylcarbamoylmethyl iminodiacetic acid labeled with technetium 99m to visualize the gallbladder and its emptying and diethylenetriamine pentaacetic acid labeled with indium 111 to visualize the stomach and its emptying was used to study 43 normal subjects and 18 patients with vagotomies [20].
  • Indium-labeled granulocyte accumulation was significantly less in ischemic myocardium in AICA riboside-treated compared with saline-treated dogs [21].
  • Myocardial accumulation of labeled lymphocytes was quantified (indium excess, IE) with a previously described and validated technique [22].
  • Single photon-emission tomography (SPECT) and indium 111-labeled monoclonal antimyosin Fab fragments were used to measure myocardial infarct size in 12 dogs, six subjected to balloon catheter-induced coronary artery occlusion for 6 hr (late reperfusion) and six subjected to occlusion with reperfusion at 2 hr (early reperfusion) [23].

Associations of indium with other chemical compounds

  • We conclude that dual-isotope SPECT with indium 111-monoclonal antimyosin antibodies and thallium-201 can accurately estimate infarct size and percentage myocardium infarcted [23].
  • The particle sizes lie in the range of 15-20 nm for the iron, 10-15 nm for the indium, 2.5-3.5 nm for gallium, and around 20 nm for zinc oxide [24].
  • These results indicate that indium chloride in 111 is a useful agent for the delineation of erythroid cellularity within bone marrow [25].
  • Growth of InP nanostructures via reaction of indium droplets with phosphide ions: synthesis of InP quantum rods and InP-TiO2 composites [26].
  • Stabilization of these electron-poorer phases through electronic tuning occurs via two different structural (redox) perturbations, either by substitution of certain indium atoms in the clusters by electron-poorer lithium atoms or by the introduction of defects and disorder in the fused cluster (III) [27].

Gene context of indium


Analytical, diagnostic and therapeutic context of indium


  1. Foot infections in diabetic patients. Decision and cost-effectiveness analyses. Eckman, M.H., Greenfield, S., Mackey, W.C., Wong, J.B., Kaplan, S., Sullivan, L., Dukes, K., Pauker, S.G. JAMA (1995) [Pubmed]
  2. Indium 111-granulocyte scanning in the assessment of disease extent and disease activity in inflammatory bowel disease. A comparison with colonoscopy, histology, and fecal indium 111-granulocyte excretion. Saverymuttu, S.H., Camilleri, M., Rees, H., Lavender, J.P., Hodgson, H.J., Chadwick, V.S. Gastroenterology (1986) [Pubmed]
  3. Early and delayed indium 111 leukocyte imaging in Crohn's disease. Navab, F., Boyd, C.M., Diner, W.C., Subramani, R., Chan, C. Gastroenterology (1987) [Pubmed]
  4. Location and activity of ulcerative and Crohn's colitis by indium 111 leukocyte scan. A prospective comparison study. Stein, D.T., Gray, G.M., Gregory, P.B., Anderson, M., Goodwin, D.A., McDougall, I.R. Gastroenterology (1983) [Pubmed]
  5. Unsuspected osteomyelitis in diabetic foot ulcers. Diagnosis and monitoring by leukocyte scanning with indium in 111 oxyquinoline. Newman, L.G., Waller, J., Palestro, C.J., Schwartz, M., Klein, M.J., Hermann, G., Harrington, E., Harrington, M., Roman, S.H., Stagnaro-Green, A. JAMA (1991) [Pubmed]
  6. Thrombin stimulates the adherence of neutrophils to human endothelial cells in vitro. Zimmerman, G.A., McIntyre, T.M., Prescott, S.M. J. Clin. Invest. (1985) [Pubmed]
  7. Somatostatin-receptor imaging of neuroendocrine gastroenteropancreatic tumors. Scherübl, H., Bäder, M., Fett, U., Hamm, B., Schmidt-Gayk, H., Koppenhagen, K., Dop, F.J., Riecken, E.O., Wiedenmann, B. Gastroenterology (1993) [Pubmed]
  8. Nonsteroidal antiinflammatory drug-induced intestinal inflammation in humans. Bjarnason, I., Zanelli, G., Smith, T., Prouse, P., Williams, P., Smethurst, P., Delacey, G., Gumpel, M.J., Levi, A.J. Gastroenterology (1987) [Pubmed]
  9. Myocyte cell damage after administration of doxorubicin or mitoxantrone in breast cancer patients assessed by indium 111 antimyosin monoclonal antibody studies. Estorch, M., Carrió, I., Martínez-Duncker, D., Berná, L., Torres, G., Alonso, C., Ojeda, B. J. Clin. Oncol. (1993) [Pubmed]
  10. Evaluation of aplastic anemia with indium chloride In 111 scanning. Horn, N.L., Bennett, L.R., Marciano, D. Arch. Intern. Med. (1980) [Pubmed]
  11. Scintigraphic detection of coronary artery thrombi in patients with acute myocardial infarction. Fox, K.A., Bergmann, S.R., Mathias, C.J., Powers, W.J., Siegel, B.A., Welch, M.J., Sobel, B.E. J. Am. Coll. Cardiol. (1984) [Pubmed]
  12. Large-volume liver metastases from neuroendocrine tumors: hepatic intraarterial 90Y-DOTA-lanreotide as effective palliative therapy. McStay, M.K., Maudgil, D., Williams, M., Tibballs, J.M., Watkinson, A.F., Caplin, M.E., Buscombe, J.R. Radiology. (2005) [Pubmed]
  13. Use of a provocation test for objective assessment of dumping syndrome in patients undergoing surgery for duodenal ulcer. Kaushik, S.P., Ralphs, D.N., Hobsley, M., Le Quesne, L.P. Am. J. Gastroenterol. (1980) [Pubmed]
  14. Electrically conducting polymers can noninvasively control the shape and growth of mammalian cells. Wong, J.Y., Langer, R., Ingber, D.E. Proc. Natl. Acad. Sci. U.S.A. (1994) [Pubmed]
  15. Functional coronary microvascular injury evident as increased permeability due to brief ischemia and reperfusion. Dauber, I.M., VanBenthuysen, K.M., McMurtry, I.F., Wheeler, G.S., Lesnefsky, E.J., Horwitz, L.D., Weil, J.V. Circ. Res. (1990) [Pubmed]
  16. Effects of transferrin-indium on cellular proliferation of a human leukemia cell line. Moran, P.L., Seligman, P.A. Cancer Res. (1989) [Pubmed]
  17. Identification of active sites in gold-catalyzed hydrogenation of acrolein. Mohr, C., Hofmeister, H., Radnik, J., Claus, P. J. Am. Chem. Soc. (2003) [Pubmed]
  18. Detection of cardiac allograft rejection and myocyte necrosis by monoclonal antibody to cardiac myosin. Allen, M.D., Tsuboi, H., Togo, T., Eary, J.F., Gordon, D., Thomas, R., Reichenbach, D.D. Transplantation (1989) [Pubmed]
  19. Colonic transit scintigraphy. A physiologic approach to the quantitative measurement of colonic transit in humans. Krevsky, B., Malmud, L.S., D'Ercole, F., Maurer, A.H., Fisher, R.S. Gastroenterology (1986) [Pubmed]
  20. Cholinergic effects on gallbladder emptying in humans. Fisher, R.S., Rock, E., Malmud, L.S. Gastroenterology (1985) [Pubmed]
  21. Increased adenosine concentration in blood from ischemic myocardium by AICA riboside. Effects on flow, granulocytes, and injury. Gruber, H.E., Hoffer, M.E., McAllister, D.R., Laikind, P.K., Lane, T.A., Schmid-Schoenbein, G.W., Engler, R.L. Circulation (1989) [Pubmed]
  22. Detection of cardiac transplant rejection with 111In-labeled lymphocytes and gamma scintigraphy. Rubin, P.J., Hartman, J.J., Hasapes, J.P., Bakke, J.E., Bergmann, S.R. Circulation (1996) [Pubmed]
  23. Measurement of infarct size and percentage myocardium infarcted in a dog preparation with single photon-emission computed tomography, thallium-201, and indium 111-monoclonal antimyosin Fab. Johnson, L.L., Lerrick, K.S., Coromilas, J., Seldin, D.W., Esser, P.D., Zimmerman, J.M., Keller, A.M., Alderson, P.O., Bigger, J.T., Cannon, P.J. Circulation (1987) [Pubmed]
  24. A general nonaqueous route to binary metal oxide nanocrystals involving a C-C bond cleavage. Pinna, N., Garnweitner, G., Antonietti, M., Niederberger, M. J. Am. Chem. Soc. (2005) [Pubmed]
  25. Bone-marrow imaging in pure red blood cell aplasia. Bunn, H.F., McNeil, B.J., Rosenthal, D.S., Krantz, S.B. Arch. Intern. Med. (1976) [Pubmed]
  26. Growth of InP nanostructures via reaction of indium droplets with phosphide ions: synthesis of InP quantum rods and InP-TiO2 composites. Nedeljković, J.M., Mićić, O.I., Ahrenkiel, S.P., Miedaner, A., Nozik, A.J. J. Am. Chem. Soc. (2004) [Pubmed]
  27. Phase stabilization through electronic tuning: electron-poorer alkali-metal-indium compounds with unprecedented In/Li clusters. Li, B., Corbett, J.D. J. Am. Chem. Soc. (2005) [Pubmed]
  28. LFA-1 is required for retention of effector CD8 T cells in mouse lungs. Thatte, J., Dabak, V., Williams, M.B., Braciale, T.J., Ley, K. Blood (2003) [Pubmed]
  29. C2-ceramide and C6-ceramide inhibited priming for enhanced release of superoxide in monocytes, but had no effect on the killing of leukaemic cells by monocytes. Nakabo, Y., Pabst, M.J. Immunology (1997) [Pubmed]
  30. Somatostatin receptor type 2 gene expression in neuroblastoma, measured by competitive RT-PCR, is related to patient survival and to somatostatin receptor imaging by indium -111-pentetreotide. Orlando, C., Raggi, C.C., Bagnoni, L., Sestini, R., Briganti, V., La Cava, G., Bernini, G., Tonini, G.P., Pazzagli, M., Serio, M., Maggi, M. Med. Pediatr. Oncol. (2001) [Pubmed]
  31. Alterations in renal heme biosynthesis during metal nephrotoxicity. Oskarsson, A., Fowler, B.A. Ann. N. Y. Acad. Sci. (1987) [Pubmed]
  32. Epidermal growth factor receptor as a target for therapy with antireceptor monoclonal antibodies. Mendelsohn, J. J. Natl. Cancer Inst. Monographs (1992) [Pubmed]
  33. Indium-labelled autologous platelets as diagnostic aid after renal transplantation. Smith, N., Chandler, S., Hawker, R.J., Hawker, L.M., Barnes, A.D. Lancet (1979) [Pubmed]
  34. Survival of patients with resistant Hodgkin's disease after polyclonal yttrium 90-labeled antiferritin treatment. Herpst, J.M., Klein, J.L., Leichner, P.K., Quadri, S.M., Vriesendorp, H.M. J. Clin. Oncol. (1995) [Pubmed]
  35. Lack of radioimmunodetection and complications associated with monoclonal anticarcinoembryonic antigen antibody cross-reactivity with an antigen on circulating cells. Dillman, R.O., Beauregard, J.C., Sobol, R.E., Royston, I., Bartholomew, R.M., Hagan, P.S., Halpern, S.E. Cancer Res. (1984) [Pubmed]
  36. Endothelial regeneration. VI. Chronic nondenuding injury in baboon vascular grafts. Reidy, M.A., Chao, S.S., Kirkman, T.R., Clowes, A.W. Am. J. Pathol. (1986) [Pubmed]
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