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Okamura, H. et al.

High-level induction of gamma interferon with various mitogens in mice pretreated with Propionibacterium acnes.

Various T-cell mitogens induced high levels of circulating gamma interferon (IFN-gamma) in mice that had been pretreated with Propionibacterium acnes. Administration of lipopolysaccharide, a B-cell mitogen, to these mice also caused pronounced production of IFN-gamma in addition to IFN-alpha and IFN-beta. The enhanced induction was most marked at about 1 week after the pretreatment.[1]

References

High-level induction of gamma interferon with various mitogens in mice pretreated with Propionibacterium acnes. Okamura, H., Kawaguchi, K., Shoji, K., Kawade, Y. Infect. Immun. (1982) [Pubmed]

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