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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Goodpasture antigen of the glomerular basement membrane: localization to noncollagenous regions of type IV collagen.

The glomerular basement membrane antigen in Goodpasture syndrome is a collagenase-resistant molecule with a monomer molecular weight of about 26,000. Type IV collagen isolated from glomerular basement membrane contains collagenase-resistant sequences within its structure. Polyacrylamide gel electrophoresis, enzyme-linked immunosorbent assay, and chemical analysis were used to demonstrate that the collagenase-resistant sequences of type IV collagen contain Goodpasture antigen.[1]

References

  1. Goodpasture antigen of the glomerular basement membrane: localization to noncollagenous regions of type IV collagen. Wieslander, J., Barr, J.F., Butkowski, R.J., Edwards, S.J., Bygren, P., Heinegård, D., Hudson, B.G. Proc. Natl. Acad. Sci. U.S.A. (1984) [Pubmed]
 
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