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MeSH Review

Glomerular Basement Membrane

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Disease relevance of Glomerular Basement Membrane


High impact information on Glomerular Basement Membrane


Chemical compound and disease context of Glomerular Basement Membrane


Biological context of Glomerular Basement Membrane


Anatomical context of Glomerular Basement Membrane


Associations of Glomerular Basement Membrane with chemical compounds


Gene context of Glomerular Basement Membrane


Analytical, diagnostic and therapeutic context of Glomerular Basement Membrane


  1. Pathogenic antibodies inhibit the binding of apolipoproteins to megalin/gp330 in passive Heymann nephritis. Kerjaschki, D., Exner, M., Ullrich, R., Susani, M., Curtiss, L.K., Witztum, J.L., Farquhar, M.G., Orlando, R.A. J. Clin. Invest. (1997) [Pubmed]
  2. Molecular cloning of the human Goodpasture antigen demonstrates it to be the alpha 3 chain of type IV collagen. Turner, N., Mason, P.J., Brown, R., Fox, M., Povey, S., Rees, A., Pusey, C.D. J. Clin. Invest. (1992) [Pubmed]
  3. Determination of the genomic structure of the COL4A4 gene and of novel mutations causing autosomal recessive Alport syndrome. Boye, E., Mollet, G., Forestier, L., Cohen-Solal, L., Heidet, L., Cochat, P., Grünfeld, J.P., Palcoux, J.B., Gubler, M.C., Antignac, C. Am. J. Hum. Genet. (1998) [Pubmed]
  4. Amyloid P component is not present in the glomerular basement membrane in Alport-type hereditary nephritis. Melvin, T., Kim, Y., Michael, A.F. Am. J. Pathol. (1986) [Pubmed]
  5. Tumor necrosis factor-alpha is expressed by glomerular visceral epithelial cells in human membranous nephropathy. Neale, T.J., Rüger, B.M., Macaulay, H., Dunbar, P.R., Hasan, Q., Bourke, A., Murray-McIntosh, R.P., Kitching, A.R. Am. J. Pathol. (1995) [Pubmed]
  6. The renal glomerulus of mice lacking s-laminin/laminin beta 2: nephrosis despite molecular compensation by laminin beta 1. Noakes, P.G., Miner, J.H., Gautam, M., Cunningham, J.M., Sanes, J.R., Merlie, J.P. Nat. Genet. (1995) [Pubmed]
  7. Collagen COL4A3 knockout: a mouse model for autosomal Alport syndrome. Cosgrove, D., Meehan, D.T., Grunkemeyer, J.A., Kornak, J.M., Sayers, R., Hunter, W.J., Samuelson, G.C. Genes Dev. (1996) [Pubmed]
  8. Antibodies to basement membrane heparan sulfate proteoglycans bind to the laminae rarae of the glomerular basement membrane (GBM) and induce subepithelial GBM thickening. Miettinen, A., Stow, J.L., Mentone, S., Farquhar, M.G. J. Exp. Med. (1986) [Pubmed]
  9. Binding specificity of serum amyloid P component for the pyruvate acetal of galactose. Hind, C.R., Collins, P.M., Renn, D., Cook, R.B., Caspi, D., Baltz, M.L., Pepys, M.B. J. Exp. Med. (1984) [Pubmed]
  10. Enhancement of glomerular immune complex deposition by a circulating polycation. Barnes, J.L., Venkatachalam, M.A. J. Exp. Med. (1984) [Pubmed]
  11. Release of glomerular heparan-35SO4 proteoglycan by heparin from glomeruli of streptozocin-induced diabetic rats. Klein, D.J., Oegema, T.R., Brown, D.M. Diabetes (1989) [Pubmed]
  12. Reduction of heparan sulphate-associated anionic sites in the glomerular basement membrane of rats with streptozotocin-induced diabetic nephropathy. van den Born, J., van Kraats, A.A., Bakker, M.A., Assmann, K.J., Dijkman, H.B., van der Laak, J.A., Berden, J.H. Diabetologia (1995) [Pubmed]
  13. Renal artery dysplasia in a patient with membranoproliferative glomerulonephritis. Leslie, B.R., Hamburger, R.J., Stilmant, M.M., Flamenbaum, W. Am. J. Med. (1979) [Pubmed]
  14. Analysis of anionic charge of the glomerular basement membrane in aminonucleoside nephrosis. Kobayashi, S., Nagase, M., Honda, N., Adachi, K., Ichinose, N., Hishida, A. Kidney Int. (1989) [Pubmed]
  15. The effect of losartan and captopril on glomerular basement membrane anionic charge in a diabetic rat model. Yavuz, D.G., Ersöz, O., Kuçükkaya, B., Budak, Y., Ahiskali, R., Ekicioglu, G., Emerk, K., Akalin, S. J. Hypertens. (1999) [Pubmed]
  16. Lectin-like activity of components extracted from human glomerular basement membrane. Gerfaux, J., Chany-Fournier, F., Bardos, P., Muh, J.P., Chany, C. Proc. Natl. Acad. Sci. U.S.A. (1979) [Pubmed]
  17. Altered gene expression and functions of mitochondria in human nephrotic syndrome. Holthöfer, H., Kretzler, M., Haltia, A., Solin, M.L., Taanman, J.W., Schägger, H., Kriz, W., Kerjaschki, D., Schlöndorff, D. FASEB J. (1999) [Pubmed]
  18. Goodpasture antigen-binding protein, the kinase that phosphorylates the goodpasture antigen, is an alternatively spliced variant implicated in autoimmune pathogenesis. Raya, A., Revert-Ros, F., Martinez-Martinez, P., Navarro, S., Rosello, E., Vieites, B., Granero, F., Forteza, J., Saus, J. J. Biol. Chem. (2000) [Pubmed]
  19. Heparanase-1 gene expression and regulation by high glucose in renal epithelial cells: a potential role in the pathogenesis of proteinuria in diabetic patients. Maxhimer, J.B., Somenek, M., Rao, G., Pesce, C.E., Baldwin, D., Gattuso, P., Schwartz, M.M., Lewis, E.J., Prinz, R.A., Xu, X. Diabetes (2005) [Pubmed]
  20. From the periphery of the glomerular capillary wall toward the center of disease: podocyte injury comes of age in diabetic nephropathy. Wolf, G., Chen, S., Ziyadeh, F.N. Diabetes (2005) [Pubmed]
  21. Stages of renal ontogenesis identified by monoclonal antibodies reactive with lymphohemopoietic differentiation antigens. Platt, J.L., LeBien, T.W., Michael, A.F. J. Exp. Med. (1983) [Pubmed]
  22. Human laminin beta2 deficiency causes congenital nephrosis with mesangial sclerosis and distinct eye abnormalities. Zenker, M., Aigner, T., Wendler, O., Tralau, T., Müntefering, H., Fenski, R., Pitz, S., Schumacher, V., Royer-Pokora, B., Wühl, E., Cochat, P., Bouvier, R., Kraus, C., Mark, K., Madlon, H., Dötsch, J., Rascher, W., Maruniak-Chudek, I., Lennert, T., Neumann, L.M., Reis, A. Hum. Mol. Genet. (2004) [Pubmed]
  23. Pathogenesis of diabetic vascular disease: evidence for the role of reduced heparan sulfate proteoglycan. Jensen, T. Diabetes (1997) [Pubmed]
  24. Glomerular basement membrane-containing immune complexes stimulate tumor necrosis factor and interleukin-1 production by human monocytes. Vissers, M.C., Fantone, J.C., Wiggins, R., Kunkel, S.L. Am. J. Pathol. (1989) [Pubmed]
  25. epsilon-Amino-lysine-bound glucose in human tissues obtained at autopsy. Increase in diabetes mellitus. Vogt, B.W., Schleicher, E.D., Wieland, O.H. Diabetes (1982) [Pubmed]
  26. Glomerulopathy in rats with streptozotocin diabetes. Accumulation of glomerular basement membrane analogous to human diabetic nephropathy. Cohen, M.P., Klein, C.V. J. Exp. Med. (1979) [Pubmed]
  27. Amyloid P-component is a constituent of normal human glomerular basement membrane. Dyck, R.F., Lockwood, C.M., Kershaw, M., McHugh, N., Duance, V.C., Baltz, M.L., Pepys, M.B. J. Exp. Med. (1980) [Pubmed]
  28. Targeted enzyme therapy of experimental glomerulonephritis in rats. White, R.B., Lowrie, L., Stork, J.E., Iskandar, S.S., Lamm, M.E., Emancipator, S.N. J. Clin. Invest. (1991) [Pubmed]
  29. Preservation of the glomerular capillary ultrafiltration coefficient during rat nephrotoxic serum nephritis by a specific leukotriene D4 receptor antagonist. Badr, K.F., Schreiner, G.F., Wasserman, M., Ichikawa, I. J. Clin. Invest. (1988) [Pubmed]
  30. Anionic sites in the glomerular basement membrane. In vivo and in vitro localization to the laminae rarae by cationic probes. Kanwar, Y.S., Farquhar, M.G. J. Cell Biol. (1979) [Pubmed]
  31. Transcriptional induction of slit diaphragm genes by Lmx1b is required in podocyte differentiation. Miner, J.H., Morello, R., Andrews, K.L., Li, C., Antignac, C., Shaw, A.S., Lee, B. J. Clin. Invest. (2002) [Pubmed]
  32. In vivo expression of putative LMX1B targets in nail-patella syndrome kidneys. Heidet, L., Bongers, E.M., Sich, M., Zhang, S.Y., Loirat, C., Meyrier, A., Broyer, M., Landthaler, G., Faller, B., Sado, Y., Knoers, N.V., Gubler, M.C. Am. J. Pathol. (2003) [Pubmed]
  33. Interleukin-12 from intrinsic cells is an effector of renal injury in crescentic glomerulonephritis. Timoshanko, J.R., Kitching, A.R., Holdsworth, S.R., Tipping, P.G. J. Am. Soc. Nephrol. (2001) [Pubmed]
  34. Inactive matrix metalloproteinase 2 is a normal constituent of human glomerular basement membrane. An immuno-electron microscopic study. Jalalah, S.M., Furness, P.N., Barker, G., Thomas, M., Hall, L.L., Bicknell, G.R., Shaw, J.A., Pringle, J.H. J. Pathol. (2000) [Pubmed]
  35. Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane. Miner, J.H., Li, C. Dev. Biol. (2000) [Pubmed]
  36. Characterization of antigens and antibody specificities involved in Heymann nephritis. Kamata, K., Baird, L.G., Erikson, M.E., Collins, A.B., McCluskey, R.T. J. Immunol. (1985) [Pubmed]
  37. Isolation and characterization of the heparan sulfate proteoglycan of the bovine glomerular basement membrane. Parthasarathy, N., Spiro, R.G. J. Biol. Chem. (1984) [Pubmed]
  38. Expression of agrin, dystroglycan, and utrophin in normal renal tissue and in experimental glomerulopathies. Raats, C.J., van den Born, J., Bakker, M.A., Oppers-Walgreen, B., Pisa, B.J., Dijkman, H.B., Assmann, K.J., Berden, J.H. Am. J. Pathol. (2000) [Pubmed]
  39. Suppression of nephrotoxic serum nephritis in rats by prostaglandin E1. Kunkel, S.L., Zanetti, M., Sapin, C. Am. J. Pathol. (1982) [Pubmed]
  40. Macromolecular organization of basement membranes. Characterization and comparison of glomerular basement membrane and lens capsule components by immunochemical and lectin affinity procedures. Mohan, P.S., Spiro, R.G. J. Biol. Chem. (1986) [Pubmed]
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