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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

An involvement of acetylcholine in object discrimination learning and memory in the marmoset.

Five marmosets (Callithrix jacchus) were tested, using a Wisconsin General Test Apparatus, on a series of junk object visual discrimination tasks, including new learning, 24-hr reversal and 24-hr retention. The effects of administering the cholinergic receptor blocking agent, scopolamine either just before or immediately after the new learning task, or just before the 24-hr reversal and retention tasks, were assessed. Results suggest that scopolamine impairs new learning and impairs the encoding of new information in long term memory. Some evidence of a mild retrieval deficit under scopolamine was also seen, while state-dependent effects were not apparent.[1]

References

  1. An involvement of acetylcholine in object discrimination learning and memory in the marmoset. Ridley, R.M., Bowes, P.M., Baker, H.F., Crow, T.J. Neuropsychologia. (1984) [Pubmed]
 
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